Laurent Groc

Publications

• Ketamine alleviates NMDA receptor hypofunction through synaptic trapping
  Frédéric Villéga, Alexandra Fernandes, Julie Jézéquel, Floriane Uyttersprot, Nathan Benac, Sarra Zenagui, Laurine Bastardo, Hélène Gréa, Delphine Bouchet, Léa Villetelle, Olivier Nicole, Véronique Rogemond, Jérôme Honnorat, Julien P. Dupuis, Laurent Groc.
  Neuron. 2024-10-01. 112(19) : 3311-3328.e9.
  10.1016/j.neuron.2024.06.028
• Synaptic rearrangement of NMDA receptors controls memory engram formation and malleability in the cortex
  Benjamin Bessières, Julien Dupuis, Laurent Groc, Bruno Bontempi, Olivier Nicole.
  Sci. Adv.. 2024-08-30. 10(35)
  10.1126/sciadv.ado1148
• APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors
  Jade Dunot, Sebastien Moreno, Carine Gandin, Paula A. Pousinha, Mascia Amici, Julien Dupuis, Margarita Anisimova, Alex Winschel, Magalie Uriot, Samuel J. Petshow, Maria Mensch, Ingrid Bethus, Camilla Giudici, Heike Hampel, Benedikt Wefers, Wolfgang Wurst, Ronald Naumann, Michael C. Ashby, Bodo Laube, Karen Zito, Jack R. Mellor, Laurent Groc, Michael Willem, Hélène Marie.
  Neuron. 2024-06-01.
  10.1016/j.neuron.2024.05.027
• NMDA receptor autoantibodies primarily impair the extrasynaptic compartment
  Zoe Jamet, Camille Mergaux, Morgane Meras, Delphine Bouchet, Frédéric Villega, Jakob Kreye, Harald Prüss, Laurent Groc.
  Brain. 2024-05-17.
  10.1093/BRAIN/AWAE163
• Converging synaptic and network dysfunctions in distinct autoimmune encephalitis
  Daniel Hunter, Mar Petit-Pedrol, Dominique Fernandes, Nathan Bénac, Catarina Rodrigues, Jakob Kreye, Mihai Ceanga, Harald Prüss, Christian Geis, Laurent Groc.
  EMBO Rep. 2024-01-22.
  10.1038/s44319-024-00056-2
• Non-canonical interplay between glutamatergic NMDA and dopamine receptors shapes synaptogenesis
  Nathan Bénac, G. Ezequiel Saraceno, Corey Butler, Nahoko Kuga, Yuya Nishimura, Taiki Yokoi, Ping Su, Takuya Sasaki, Mar Petit-Pedrol, Rémi Galland, Vincent Studer, Fang Liu, Yuji Ikegaya, Jean-Baptiste Sibarita, Laurent Groc.
  Nat Commun. 2024-01-02. 15(1)
  10.1038/s41467-023-44301-z
• GluN3A subunit tunes NMDA receptor synaptic trafficking and content during postnatal brain development
  Inmaculada M. González-González, John A. Gray, Joana Ferreira, María Jose Conde-Dusman, Delphine Bouchet, Isabel Perez-Otaño, Laurent Groc.
  Cell Reports. 2023-05-01. 42(5) : 112477.
  10.1016/j.celrep.2023.112477
• Nanoscale and functional heterogeneity of the hippocampal extracellular space
  Diego Grassi, Agata Idziak, Antony Lee, Ivo Calaresu, Jean-Baptiste Sibarita, Laurent Cognet, U. Valentin Nägerl, Laurent Groc.
  Cell Reports. 2023-05-01. 42(5) : 112478.
  10.1016/j.celrep.2023.112478
• Cognitive and psychiatric features of anti-NMDA receptor encephalitis
  Frederic Villéga, Harald Prüss, Ludger Tebartz van Elst, Laurent Groc.
  The Lancet Neurology. 2022-10-01. 21(10) : 861-862.
  10.1016/S1474-4422(22)00349-0
• Near-Infrared Carbon Nanotube Tracking Reveals the Nanoscale Extracellular Space around Synapses
  Chiara Paviolo, Joana S. Ferreira, Antony Lee, Daniel Hunter, Ivo Calaresu, Somen Nandi, Laurent Groc, Laurent Cognet.
  Nano Lett.. 2022-08-29.
  10.1021/acs.nanolett.1c04259
• Multi-Dimensional Spectral Single Molecule Localization Microscopy
  Corey Butler, G Ezequiel Saraceno, Adel Kechkar, Nathan Bénac, Vincent Studer, Julien P. Dupuis, Laurent Groc, Rémi Galland, Jean-Baptiste Sibarita.
  Front. Bioinform.. 2022-03-04. 2
  10.3389/fbinf.2022.813494
• CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation
  Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi.
  Nat Neurosci. 2021-04-29.
  10.1038/s41593-021-00843-3
• A Bottom-Up Approach to Red-Emitting Molecular-Based Nanoparticles with Natural Stealth Properties and their Use for Single-Particle Tracking Deep in Brain Tissue.
  Rosendale M, Flores J, Paviolo C, Pagano P, Daniel J, Ferreira J, Verlhac JB, Groc L, Cognet L, Blanchard-Desce M..
  Advanced Materialds. 2021-04-21.
  10.1002/adma.202006644
• Regulation of membrane NMDA receptors by dynamics and protein interactions
  Mar Petit-Pedrol, Laurent Groc.
  Journal of Cell Biology. 2020-12-18. 220(1)
  10.1083/jcb.202006101
• CaMKII activation triggers persistent formation and segregation of postsynaptic liquid phase
  Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi.
  . 2020-11-26.
  10.1101/2020.11.25.397091
• Distance-dependent regulation of NMDAR nanoscale organization along hippocampal neuron dendrites
  Joana S. Ferreira, Julien P. Dupuis, Blanka Kellermayer, Nathan Bénac, Constance Manso, Delphine Bouchet, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Laurent Groc.
  Proc Natl Acad Sci USA. 2020-09-14. : 201922477.
  10.1073/pnas.1922477117
• Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
  Federico N. Soria, Chiara Paviolo, Evelyne Doudnikoff, Marie-Laure Arotcarena, Antony Lee, Noémie Danné, Amit Kumar Mandal, Philippe Gosset, Benjamin Dehay, Laurent Groc, Laurent Cognet, Erwan Bezard.
  Nat Commun. 2020-07-10. 11(1)
  10.1038/s41467-020-17328-9
• Human endogenous retroviral protein triggers deficit in glutamate synapse maturation and behaviors associated with psychosis
  E. M. Johansson, D. Bouchet, R. Tamouza, P. Ellul, AS. Morr, E. Avignone, R. Germi, M. Leboyer, H. Perron, L. Groc.
  Sci. Adv.. 2020-07-01. 6(29) : eabc0708.
  10.1126/sciadv.abc0708
• Linking glutamate receptor movements and synapse function
  Laurent Groc, Daniel Choquet.
  Science. 2020-06-11. 368(6496) : eaay4631.
  10.1126/science.aay4631
• Fluorescent sp3 Defect-Tailored Carbon Nanotubes Enable NIR-II Single Particle Imaging in Live Brain Slices at Ultra-Low Excitation Doses
  Amit Kumar Mandal, Xiaojian Wu, Joana S. Ferreira, Mijin Kim, Lyndsey R. Powell, Hyejin Kwon, Laurent Groc, YuHuang Wang, Laurent Cognet.
  Sci Rep. 2020-03-24. 10(1)
  10.1038/s41598-020-62201-w
• Aquaporin-4 Surface Trafficking Regulates Astrocytic Process Motility and Synaptic Activity in Health and Autoimmune Disease.
  Silvia Ciappelloni, Delphine Bouchet, Nadège Dubourdieu, Eric Boué-Grabot, Blanka Kellermayer, Constance Manso, Romain Marignier, Stéphane H.R. Oliet, Thomas Tourdias, Laurent Groc.
  Cell Reports. 2019-06-01. 27(13) : 3860-3872.e4.
  10.1016/j.celrep.2019.05.097
• Self-Interference (SELFI) Microscopy for Live Super-Resolution Imaging and Single Particle Tracking in 3D
  Jeanne Linarès-Loyez, Joana S. Ferreira, Olivier Rossier, Brahim Lounis, Gregory Giannone, Laurent Groc, Laurent Cognet, Pierre Bon.
  Front. Phys.. 2019-05-08. 7
  10.3389/fphy.2019.00068
• Surface trafficking of neurotransmitter receptor: comparison between single-molecule/quantum dot strategies
  Groc L, Lafourcade M, Heine M, Renner M, Racine V, Sibarita JB, Lounis B, Choquet D, Cognet L..
  J Neurosci.. 2007 Nov 14. 27(46) : 12433-7.
  27/46/12433 [pii]10.1523/JNEUROSCI.3349-07.2007
• Surface trafficking of neurotransmitter receptors: From cultured neurons to intact brain preparations
  Julien P. Dupuis, Laurent Groc.
  Neuropharmacology. 2019-05-01. : 107642.
  10.1016/j.neuropharm.2019.05.019
• Single nanoparticle tracking of N-methyl-D-aspartate receptors in cultured and intact brain tissue
  Varela JA, Ferreira JS, Dupuis JP, Durand P, Bouchet D, Groc L..
  Neurophotonics. 2016-07-12. 3(4)
  10.1117/1.NPh.3.4.041808]
• Nanoscale exploration of the extracellular space in the live brain by combining single carbon nanotube tracking and super-resolution imaging analysis
  Chiara Paviolo, Federico N. Soria, Joana S. Ferreira, Antony Lee, Laurent Groc, Erwan Bezard, Laurent Cognet.
  Methods. 2019-03-09.
  10.1016/j.ymeth.2019.03.005
• Pathogenicity of Antibodies against NMDA Receptor: Molecular Insights into Autoimmune Psychosis.
  J. Jézéquel, E.M. Johansson, M. Leboyer, L. Groc.
  Trends in Neurosciences. 2018-08-01. 41(8) : 502-511.
  10.1016/j.tins.2018.05.002
• Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients
  Julie Jézéquel, Emily M. Johansson, Julien P. Dupuis, Véronique Rogemond, Hélène Gréa, Blanka Kellermayer, Nora Hamdani, Emmanuel Le Guen, Corentin Rabu, Marilyn Lepleux, Marianna Spatola, Elodie Mathias, Delphine Bouchet, Amy J. Ramsey, Robert H. Yolken, Ryad Tamouza, Josep Dalmau, Jérôme Honnorat, Marion Leboyer, Laurent Groc.
  Nat Commun. 2017-11-27. 8(1)
  10.1038/s41467-017-01700-3
• Dynamics of surface neurotransmitter receptors and transporters in glial cells: Single molecule insights
  Silvia Ciappelloni, Ciaran Murphy-Royal, Julien P. Dupuis, Stéphane H.R. Oliet, Laurent Groc.
  Cell Calcium. 2017-11-01. 67 : 46-52.
  10.1016/j.ceca.2017.08.009
• Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice
  Elisabetta Aloisi, Katy Le Corf, Julien Dupuis, Pei Zhang, Melanie Ginger, Virginie Labrousse, Michela Spatuzza, Matthias Georg Haberl, Lara Costa, Ryuichi Shigemoto, Anke Tappe-Theodor, Filippo Drago, Pier Vincenzo Piazza, Christophe Mulle, Laurent Groc, Lucia Ciranna, Maria Vincenza Catania, Andreas Frick.
  Nat Commun. 2017-10-24. 8(1)
  10.1038/s41467-017-01191-2
• Single nanoparticle tracking: A method for investigating the surface dynamics of glutamate receptors
  Julien Dupuis, François Maingret, Laurent Groc.
  Neuromethods. 2017-09-22. : 29-50.
  10.1007/978-1-4939-7228-9_2
• Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses
  Joana S Ferreira, Thomas Papouin, Laurent Ladépêche, Andrea Yao, Valentin C Langlais, Delphine Bouchet, Jérôme Dulong, Jean-Pierre Mothet, Silvia Sacchi, Loredano Pollegioni, Pierre Paoletti, Stéphane Henri Richard Oliet, Laurent Groc.
  eLife. 2017-06-09. 6
  10.7554/eLife.25492
• Astroglial glutamate transporters in the brain: Regulating neurotransmitter homeostasis and synaptic transmission
  Ciaran Murphy-Royal, Julien Dupuis, Laurent Groc, Stéphane H. R. Oliet.
  Journal of Neuroscience Research. 2017-02-02. 95(11) : 2140-2151.
  10.1002/jnr.24029
• Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain
  Antoine G. Godin, Juan A. Varela, Zhenghong Gao, Noémie Danné, Julien P. Dupuis, Brahim Lounis, Laurent Groc, Laurent Cognet.
  Nature Nanotech. 2016-11-21. 12(3) : 238-243.
  10.1038/nnano.2016.248
• Co-activation of VEGF and NMDA receptors promotes synaptic targeting of AMPA receptors
  P De Rossi, E Harde, J P Dupuis, L Martin, N Chounlamountri, M Bardin, C Watrin, C Benetollo, K Pernet-Gallay, H J Luhmann, J Honnorat, G Malleret, L Groc, A Acker-Palmer, P A Salin, C Meissirel.
  Mol Psychiatry. 2016-11-16. 21(12) : 1647-1647.
  10.1038/mp.2016.215
• Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
  Juan A. Varela, Julien P. Dupuis, Laetitia Etchepare, Agnès Espana, Laurent Cognet, Laurent Groc.
  Nat Commun. 2016-03-14. 7(1)
  10.1038/ncomms10947
• Single nanoparticle tracking of surface ion channels and receptors in brain cells
  Juan Varela, Julien Dupuis, Laurent Groc.
  Neuromethods. 2016-01-01. : 49-58.
  10.1007/978-1-4939-3064-7_5
• Surface dynamics of GluN2B-NMDA receptors controls plasticity of maturing glutamate synapses
  J. P. Dupuis, L. Ladepeche, H. Seth, L. Bard, J. Varela, L. Mikasova, D. Bouchet, V. Rogemond, J. Honnorat, E. Hanse, L. Groc.
  The EMBO Journal. 2014-03-03. 33(8) : 842-861.
  10.1002/embj.201386356
• Surface trafficking of NMDA receptors: Gathering from a partner to another
  Laurent Ladépêche, Julien Pierre Dupuis, Laurent Groc.
  Seminars in Cell & Developmental Biology. 2014-03-01. 27 : 3-13.
  10.1016/j.semcdb.2013.10.005
• Regulation of AMPA receptor surface trafficking and synaptic plasticity by a cognitive enhancer and antidepressant molecule
  H Zhang, L-A Etherington, A-S Hafner, D Belelli, F Coussen, P Delagrange, F Chaouloff, M Spedding, J J Lambert, D Choquet, L Groc.
  Mol Psychiatry. 2012-06-26. 18(4) : 471-484.
  10.1038/mp.2012.80
• Temporal modulation of hippocampal excitatory transmission by corticosteroids and stress
  Francis Chaouloff, Laurent Groc.
  Frontiers in Neuroendocrinology. 2011-01-01. 32(1) : 25-42.
  10.1016/j.yfrne.2010.07.004
• Stress, corticosteroids and excitatory neurotransmission
  Laurent Groc, Francis Chaouloff.
  Future Neurology. 2008-11-01. 3(6) : 623-626.
  10.2217/14796708.3.6.623
• Lateral diffusion of excitatory neurotransmitter receptors during synaptogenesis
  Laurent Groc, Martin Heine, Laurent Cognet, Brahim Lounis, Daniel Choquet.
  Molecular Mechanisms of Synaptogenesis. . : 221-232.
  10.1007/978-0-387-32562-0_16