Yann Humeau

Publications

• CA3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation
  Hajer El Oussini, Chun-Lei Zhang, Urielle François, Cecilia Castelli, Aurélie Lampin-Saint-Amaux, Marilyn Lepleux, Pablo Molle, Legeolas Velez, Cyril Dejean, Frederic Lanore, Cyril Herry, Daniel Choquet, Yann Humeau.
  Nat Commun. 2023-12-14. 14(1)
  10.1038/s41467-023-42969-x
• Axo-axonic cells in neuropsychiatric disorders: a systematic review
  Juliette Vivien, Anass El Azraoui, Cloé Lheraux, Frederic Lanore, Bruno Aouizerate, Cyril Herry, Yann Humeau, Thomas C. M. Bienvenu.
  Front. Cell. Neurosci.. 2023-06-26. 17
  10.3389/fncel.2023.1212202
• Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice
  Marta Prieto, Alessandra Folci, Gwénola Poupon, Sara Schiavi, Valeria Buzzelli, Marie Pronot, Urielle François, Paula Pousinha, Norma Lattuada, Sophie Abelanet, Sara Castagnola, Magda Chafai, Anouar Khayachi, Carole Gwizdek, Frédéric Brau, Emmanuel Deval, Maura Francolini, Barbara Bardoni, Yann Humeau, Viviana Trezza, Stéphane Martin.
  Nat Commun. 2021-03-10. 12(1)
  10.1038/s41467-021-21820-1
• The integration of Gaussian noise by long-range amygdala inputs in frontal circuit promotes fear learning in mice
  Mattia Aime, Elisabete Augusto, Vladimir Kouskoff, Tiago Campelo, Christelle Martin, Yann Humeau, Nicolas Chenouard, Frederic Gambino.
  eLife. 2020-11-30. 9
  10.7554/elife.62594
• A proline-rich motif on VGLUT1 reduces synaptic vesicle super-pool and spontaneous release frequency
  Xiao Min Zhang, Urielle François, Kätlin Silm, Maria Florencia Angelo, Maria Victoria Fernandez-Busch, Mona Maged, Christelle Martin, Véronique Bernard, Fabrice P Cordelières, Melissa Deshors, Stéphanie Pons, Uwe Maskos, Alexis Pierre Bemelmans, Sonja M Wojcik, Salah El Mestikawy, Yann Humeau, Etienne Herzog.
  eLife. 2019-10-30. 8
  10.7554/eLife.50401
• The next generation of approaches to investigate the link between synaptic plasticity and learning
  Yann Humeau, Daniel Choquet.
  Nat Neurosci. 2019-09-02. 22(10) : 1536-1543.
  10.1038/s41593-019-0480-6
• Non-linear dendritic integration in frontal circuits shapes sensory discrimination in rodents
  Mattia Aime, Elisabete Augusto, Vladimir Kouskoff, Christelle Martin, Yann Humeau, Nicolas Chenouard, Frédéric Gambino.
  . 2019-03-06.
  10.1101/569137
• Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models
  Hongyu Zhang, Chunlei Zhang, Jean Vincent, Diana Zala, Caroline Benstaali, Matthieu Sainlos, Dolors Grillo-Bosch, Sophie Daburon, Françoise Coussen, Yoon Cho, Denis J. David, Frederic Saudou, Yann Humeau, Daniel Choquet.
  Nat Commun. 2018-10-15. 9(1)
  10.1038/s41467-018-06675-3
• Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors.
  A. C. Penn, C. L. Zhang, F. Georges, L. Royer, C. Breillat, E. Hosy, J. D. Petersen, Y. Humeau, D. Choquet.
  Nature. 2017-09-13. 549(7672) : 384-388.
  10.1038/nature23658
• Profiling olfactory stem cells from living patients identifies miRNAs relevant for autism pathophysiology.
  Nguyen LS, Lepleux M, Makhlouf M, Martin C, Fregeac J, Siquier-Pernet K, Philippe A, Feron F, Gepner B, Rougeulle C, Humeau Y, Colleaux L.
  Mol Autism.. 2016-01-08. 7(1)
  10.1186/s13229-015-0064-6
• The hippocampo-amygdala control of contextual fear expression is affected in a model of intellectual disability
  Chun-Lei Zhang, Xander Houbaert, Marilyn Lepleux, Melissa Deshors, Elisabeth Normand, Frédéric Gambino, Etienne Herzog, Yann Humeau.
  Brain Struct Funct. 2014-08-27. 220(6) : 3673-3682.
  10.1007/s00429-014-0882-x
• Coronin 1 Regulates Cognition and Behavior through Modulation of cAMP/Protein Kinase A Signaling
  Rajesh Jayachandran, Xiaolong Liu, Somdeb BoseDasgupta, Philipp Müller, Chun-Lei Zhang, Despina Moshous, Vera Studer, Jacques Schneider, Christel Genoud, Catherine Fossoud, Frédéric Gambino, Malik Khelfaoui, Christian Müller, Deborah Bartholdi, Helene Rossez, Michael Stiess, Xander Houbaert, Rolf Jaussi, Daniel Frey, Richard A. Kammerer, Xavier Deupi, Jean-Pierre de Villartay, Andreas Lüthi, Yann Humeau, Jean Pieters.
  PLoS Biol. 2014-03-25. 12(3) : e1001820.
  10.1371/journal.pbio.1001820
• Lack of the presynaptic RhoGAP protein oligophrenin1 leads to cognitive disabilities through dysregulation of the cAMP/PKA signalling pathway
  M. Khelfaoui, F. Gambino, X. Houbaert, B. Ragazzon, C. Muller, M. Carta, F. Lanore, B. N. Srikumar, P. Gastrein, M. Lepleux, C.-L. Zhang, M. Kneib, B. Poulain, S. Reibel-Foisset, N. Vitale, J. Chelly, P. Billuart, A. Luthi, Y. Humeau.
  Philosophical Transactions of the Royal Society B: Biological Sciences. 2013-12-02. 369(1633) : 20130160-20130160.
  10.1098/rstb.2013.0160
• In vivo evidence that TRAF4 is required for central nervous system myelin homeostasis
  Sébastien Blaise, Marie Kneib, Adrien Rousseau, Frederic Gambino, Marie-Pierre Chenard, Nadia Messadeq, Martine Muckenstrum, Fabien Alpy, Catherine Tomasetto, Yann Humeau, Marie-Christine Rio.
  PLoS ONE. 2012-02-17. 7(2) : e30917.
  10.1371/journal.pone.0030917
• Forebrain deletion of αGDI in adult mice worsens the pre-synaptic deficit at cortico-lateral amygdala synaptic connections
  Veronica Bianchi, Frédéric Gambino, Luca Muzio, Daniela Toniolo, Yann Humeau, Patrizia D'Adamo.
  PLoS ONE. 2012-01-23. 7(1) : e29763.
  10.1371/journal.pone.0029763
• The coffin-lowry syndrome-associated protein RSK2 and neurosecretion
  M. Zeniou-Meyer, F. Gambino, Mohamed-Raafet Ammar, Y. Humeau, N. Vitale.
  Cell Mol Neurobiol. 2010-11-01. 30(8) : 1401-1406.
  10.1007/s10571-010-9578-9
• Synaptic maturation at cortical projections to the lateral amygdala in a mouse model of rett syndrome
  Frédéric Gambino, Malik Khelfaoui, Bernard Poulain, Thierry Bienvenu, Jamel Chelly, Yann Humeau.
  PLoS ONE. 2010-07-02. 5(7) : e11399.
  10.1371/journal.pone.0011399
• IL1RAPL1 controls inhibitory networks during cerebellar development in mice
  Frédéric Gambino, Marie Kneib, Alice Pavlowsky, Henriette Skala, Stéphane Heitz, Nicolas Vitale, Bernard Poulain, Malik Khelfaoui, Jamel Chelly, Pierre Billuart, Yann Humeau.
  European Journal of Neuroscience. 2009-10-01. 30(8) : 1476-1486.
  10.1111/j.1460-9568.2009.06975.x
• L-type voltage-dependent Ca2+ channels mediate expression of presynaptic LTP in amygdala
  Elodie Fourcaudot, Frederic Gambino, Guillaume Casassus, Bernard Poulain, Yann Humeau, Andreas Lüthi.
  Nat Neurosci. 2009-08-02. 12(9) : 1093-1095.
  10.1038/nn.2378
• Amygdala Inhibitory Circuits and the Control of Fear Memory
  Ingrid Ehrlich, Yann Humeau, François Grenier, Stephane Ciocchi, Cyril Herry, Andreas Lüthi.
  Neuron. 2009-06-01. 62(6) : 757-771.
  10.1016/j.neuron.2009.05.026
• X-linked mental retardation: focus on synaptic function and plasticity
  Yann Humeau, Frédéric Gambino, Jamel Chelly, Nicolas Vitale.
  Journal of Neurochemistry. 2009-04-01. 109(1) : 1-14.
  10.1111/j.1471-4159.2009.05881.x
• cAMP/PKA signaling and RIM1α mediate presynaptic LTP in the lateral amygdala
  E. Fourcaudot, F. Gambino, Y. Humeau, G. Casassus, H. Shaban, B. Poulain, A. Luthi.
  Proceedings of the National Academy of Sciences. 2008-09-24. 105(39) : 15130-15135.
  10.1073/pnas.0806938105
• IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation
  F. Gambino, A. Pavlowsky, A. Begle, J.-L. Dupont, N. Bahi, R. Courjaret, R. Gardette, H. Hadjkacem, H. Skala, B. Poulain, J. Chelly, N. Vitale, Y. Humeau.
  Proceedings of the National Academy of Sciences. 2007-05-14. 104(21) : 9063-9068.
  10.1073/pnas.0701133104
• Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition
  Hamdy Shaban, Yann Humeau, Cyril Herry, Guillaume Cassasus, Ryuichi Shigemoto, Stephane Ciocchi, Samuel Barbieri, Herman van der Putten, Klemens Kaupmann, Bernhard Bettler, Andreas Lüthi.
  Nat Neurosci. 2006-07-02. 9(8) : 1028-1035.
  10.1038/nn1732
• Dendritic Spine Heterogeneity Determines Afferent-Specific Hebbian Plasticity in the Amygdala
  Yann Humeau, Cyril Herry, Nicola Kemp, Hamdy Shaban, Elodie Fourcaudot, Stephanie Bissière, Andreas Lüthi.
  Neuron. 2005-01-01. 45(1) : 119-131.
  10.1016/j.neuron.2004.12.019