Philippe De Deurwaerdere

Publications

• Classical psychedelics’ action on brain monoaminergic systems
  Jasmine Jade Butler, Daria Ricci, Chloé Aman, Anna Beyeler, Philippe De Deurwaerdère.
  The International Journal of Biochemistry & Cell Biology. 2024-09-01. : 106669.
  10.1016/j.biocel.2024.106669
• Serotonergic neurons are involved in the counter-regulatory response to hypoglycemia.
  Hugo Martin, Adeline Coursan, Justine Lallement, Mathieu Di Miceli, Janany Kandiah, Ilyès Raho, Jasmine Buttler, Jean‐Philippe Guilloux, Philippe De Deurwaerdere, Sophie Layé, Vanessa H. Routh, Bruno P. Guiard, Christophe Magnan, Céline Cruciani‐Guglielmacci, Xavier Fioramonti.
  J Neuroendocrinology. 2023-10-19.
  10.1111/jne.13344
• Limiting Monoamines Degradation Increases L-DOPA Pro-Locomotor Action in Newborn Rats
  Inès Khsime, Marie Boulain, Abderrahman Fettah, Abdeslam Chagraoui, Gilles Courtand, Philippe De Deurwaerdère, Laurent Juvin, Grégory Barrière.
  IJMS. 2023-09-29. 24(19) : 14747.
  10.3390/ijms241914747
• Insulin modulates emotional behavior through a serotonin-dependent mechanism
  Hugo Martin, Sébastien Bullich, Maud Martinat, Mathilde Chataigner, Mathieu Di Miceli, Vincent Simon, Samantha Clark, Jasmine Butler, Mareike Schell, Simran Chopra, Francis Chaouloff, Andre Kleinridders, Daniela Cota, Philippe De Deurwaerdere, Luc Pénicaud, Sophie Layé, Bruno P. Guiard, Xavier Fioramonti.
  Mol Psychiatry. 2022-10-07.
  10.1038/S41380-022-01812-3
• Deleting Snord115 genes in mice remodels monoaminergic systems activity in the brain toward cortico-subcortical imbalances
  Virginie Marty, Jasmine J Butler, Basile Coutens, Oumaima Chargui, Abdeslam Chagraoui, Bruno P Guiard, Philippe De Deurwaerdère, Jérôme Cavaillé.
  Human Molecular Genetics. 2022-08-11.
  10.1093/HMG/DDAC139
• Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain
  Franck Aby, Louis-Etienne Lorenzo, Zoé Grivet, Rabia Bouali-Benazzouz, Hugo Martin, Stéphane Valerio, Sara Whitestone, Dominique Isabel, Walid Idi, Otmane Bouchatta, Philippe De Deurwaerdere, Antoine G. Godin, Cyril Herry, Xavier Fioramonti, Marc Landry, Yves De Koninck, Pascal Fossat.
  Sci. Adv.. 2022-07-29. 8(30)
  10.1126/sciadv.abo0689
• Cannabinoid 1/2 Receptor Activation Induces Strain-Dependent Behavioral and Neurochemical Changes in Genetic Absence Epilepsy Rats From Strasbourg and Non-epileptic Control Rats
  Philippe De Deurwaerdère, Maurizio Casarrubea, Daniel Cassar, Manuela Radic, Emilie Puginier, Abdeslam Chagraoui, Giuseppe Crescimanno, Vincenzo Crunelli, Giuseppe Di Giovanni.
  Front. Cell. Neurosci.. 2022-05-23. 16
  10.3389/FNCEL.2022.886033
• Pathophysiology of the Serotonin System in the Nervous System and Beyond
  Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  IJMS. 2022-04-25. 23(9) : 4712.
  10.3390/ijms23094712
• Neurobiological and Pharmacological Perspectives of D3 Receptors in Parkinson’s Disease
  Abdeslam Chagraoui, Giuseppe Di Giovanni, Philippe De Deurwaerdère.
  Biomolecules. 2022-02-01. 12(2) : 243.
  10.3390/biom12020243
• Nicotine modulation of the lateral habenula/ventral tegmental area circuit dynamics: An electrophysiological study in rats
  Massimo Pierucci, Francis Delicata, Roberto Colangeli, Antonella Marino Gammazza, Alessandro Pitruzzella, Maurizio Casarrubea, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  Neuropharmacology. 2022-01-01. 202 : 108859.
  10.1016/J.NEUROPHARM.2021.108859
• Simulated Microgravity Subtlety Changes Monoamine Function across the Rat Brain
  Alexandra Gros, Léandre Lavenu, Jean-Luc Morel, Philippe De Deurwaerdère.
  IJMS. 2021-10-29. 22(21) : 11759.
  10.3390/ijms222111759
• L‐DOPA and 5‐HTP modulation of air‐stepping in newborn rats
  Marie Boulain, Wei Yuan, Zied Oueghlani, Inès Khsime, Vianney Salvi, Gilles Courtand, Christophe Halgand, Didier Morin, Philippe Deurwaerdere, Grégory Barrière, Laurent Juvin.
  J Physiol. 2021-09-05. 599(19) : 4455-4476.
  10.1113/jp281983
• Dopamine D3 Receptor: Contemporary Views of Its Function and Pharmacology for Neuropsychiatric Diseases
  Philippe De Deurwaerdère, Abdeslam Chagraoui.
  Biomolecules. 2021-05-11. 11(5) : 713.
  10.3390/biom11050713
• Lateral Habenula 5-HT_2C Receptor Function Is Altered by Acute and Chronic Nicotine Exposures
  Cristiano Bombardi, Francis Delicata, Claudio Tagliavia, Annamaria Grandis, Massimo Pierucci, Antonella Marino Gammazza, Maurizio Casarrubea , Philippe De Deurwaerdère and Giuseppe Di Giovanni.
  Int. J. Mol. Sci. 2021-04-30.
  10.3390/ijms22094775
• Multiple facets of serotonergic modulation.
  Anna Beyeler, Anes Ju, Abdeslam Chagraoui, Lise Cuvelle, Maxime Teixeira, Giuseppe Di Giovanni, Philippe De Deurwaerdère.
  Progress in Brain Research. 2021-01-01. : 3-39.
  10.1016/bs.pbr.2021.02.002
• 5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance Part B Preface
  Giuseppe Di Giovanni, Philippe De Deurwaerdere.
  Progress in Brain Research. 2021-01-01. : xix.
  10.1016/S0079-6123(21)00083-2
• 5-HT interaction with other neurotransmitters: An overview
  Philippe De Deurwaerdere, Giuseppe Di Giovanni.
  Progress in Brain Research. 2021-01-01. : 1-5.
  10.1016/BS.PBR.2021.01.001
• Serotonergic control of the glutamatergic neurons of the subthalamic nucleus
  Luisa Ugedo, Philippe De Deurwaerdère.
  Progress in Brain Research. 2021-01-01. : 423-462.
  10.1016/BS.PBR.2020.11.003
• Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics
  Cristiano Bombardi, Annamaria Grandis, Nela Pivac, Marina Sagud, Guillaume Lucas, Abdeslam Chagraoui, Valérie Lemaire-Mayo, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  Progress in Brain Research. 2021-01-01. : 83-158.
  10.1016/BS.PBR.2021.01.031
• Serotonin/dopamine interaction: Electrophysiological and neurochemical evidence
  Philippe De Deurwaerdère, Abdeslam Chagraoui, Giuseppe Di Giovanni.
  Progress in Brain Research. 2021-01-01. : 161-264.
  10.1016/BS.PBR.2021.02.001
• Serotonin research: Crossing scales and boundaries
  Giuseppe Di Giovanni, Philippe De Deurwaerdère.
  Neuropharmacology. 2020-12-01. 181 : 108340.
  10.1016/J.NEUROPHARM.2020.108340
• Editorial: Contemporary Perspective on 5-HT2C Receptor Function and Its Pharmacological Targeting
  Philippe De Deurwaerdère, Abdeslam Chagraoui, Kathryn A. Cunningham.
  Front. Pharmacol.. 2020-11-23. 11
  10.3389/FPHAR.2020.606414
• A Subset of Purposeless Oral Movements Triggered by Dopaminergic Agonists Is Modulated by 5-HT_2C Receptors in Rats: Implication of the Subthalamic Nucleus
  Mélanie Lagière, Marion Bosc, Sara Whitestone, Abdelhamid Benazzouz, Abdeslam Chagraoui, Mark J. Millan, Philippe De Deurwaerdère.
  IJMS. 2020-11-12. 21(22) : 8509.
  10.3390/ijms21228509
• Mediterranean Neuroscience Methods 2019.
  Philippe De Deurwaerdère, Salvatore Galati, Giuseppe Di Giovanni.
  Journal of Neuroscience Methods. 2020-11-01. : 109010.
  10.1016/j.jneumeth.2020.109010
• Editorial: Non-Dopaminergic Systems in Parkinson’s Disease
  Cristina Miguelez, Philippe De Deurwaerdère, Véronique Sgambato.
  Front. Pharmacol.. 2020-09-11. 11
  10.3389/FPHAR.2020.593822
• Chronic Administration of Fipronil Heterogeneously Alters the Neurochemistry of Monoaminergic Systems in the Rat Brain
  Rahul Bharatiya, Abdeslam Chagraoui, Salomé De Deurwaerdere, Antonio Argiolas, Maria Rosaria Melis, Fabrizio Sanna, Philippe De Deurwaerdere.
  IJMS. 2020-08-09. 21(16) : 5711.
  10.3390/ijms21165711
• Lorcaserin Alters Serotonin and Noradrenaline Tissue Content and Their Interaction With Dopamine in the Rat Brain
  Giuseppe Di Giovanni, Rahul Bharatiya, Emilie Puginier, Marta Ramos, Salomé De Deurwaerdère, Abdeslam Chagraoui, Philippe De Deurwaerdère.
  Front. Pharmacol.. 2020-06-30. 11
  10.3389/fphar.2020.00962
• Serotonin in Health and Disease
  Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  IJMS. 2020-05-15. 21(10) : 3500.
  10.3390/ijms21103500
• The Noradrenergic System in Parkinson’s Disease
  Elena Paredes-Rodriguez, Sergio Vegas-Suarez, Teresa Morera-Herreras, Philippe De Deurwaerdere, Cristina Miguelez.
  Front. Pharmacol.. 2020-04-08. 11
  10.3389/fphar.2020.00435
• Lorcaserin bidirectionally regulates dopaminergic function site-dependently and disrupts dopamine brain area correlations in rats
  Philippe De Deurwaerdère, Marta Ramos, Rahul Bharatiya, Emilie Puginier, Abdeslam Chagraoui, Julien Manem, Eleonora Cuboni, Massimo Pierucci, Gabriele Deidda, Maurizio Casarrubea, Giuseppe Di Giovanni.
  Neuropharmacology. 2020-04-01. 166 : 107915.
  10.1016/j.neuropharm.2019.107915
• The pesticide fipronil injected into the substantia nigra of male rats decreases striatal dopamine content: A neurochemical, immunohistochemical and behavioral study
  Rahul Bharatiya, Jessica Bratzu, Carla Lobina, Giulia Corda, Cristina Cocco, Philippe De Deurwaerdere, Antonio Argiolas, Maria Rosaria Melis, Fabrizio Sanna.
  Behavioural Brain Research. 2020-04-01. 384 : 112562.
  10.1016/j.bbr.2020.112562
• Acute and chronic nicotine exposures differentially affect central serotonin 2A receptor function: Focus on the lateral habenula
  Cristiano Bombardi, Francis Delicata, Claudio Tagliavia, Massimo Pierucci, Gabriele Deidda, Maurizio Casarrubea, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  IJMS. 2020-03-09. 21(5) : 1873.
  10.3390/ijms21051873
• Serotonin in Animal Cognition and Behavior
  Julien Bacqué-Cazenave, Rahul Bharatiya, Grégory Barrière, Jean-Paul Delbecque, Nouhaila Bouguiyoud, Giuseppe Di Di Giovanni, Daniel Cattaert, Philippe De Deurwaerdère.
  IJMS. 2020-02-28. 21(5) : 1649.
  10.3390/ijms21051649
• Old neurochemical markers, new functional directions?
  Philippe De Deurwaerdere, Silvana Gaetani, Roxanne A. Vaughan.
  J. Neurochem.. 2020-01-09.
  10.1111/jnc.14929
• L-DOPA in Parkinson’s Disease: Looking at the « False » Neurotransmitters and Their Meaning.
  Chagraoui A, Boulain M, Juvin L, Anouar Y, Barrière G, Deurwaerdère P.
  Int J Mol Sci.. 2019 Dec 31. 21(11)
  10.3390/ijms21010294.
• Constitutive activity of 5-HT receptors: Factual analysis
  Philippe De Deurwaerdère, Rahul Bharatiya, Abdeslam Chagraoui, Giuseppe Di Giovanni.
  Neuropharmacology. 2020-01-01. : 107967.
  10.1016/j.neuropharm.2020.107967
• Serotonergic control of excitability: from neuron to networks
  Giuseppe Di Giovanni, Abdeslam Chagraoui, Rahul Bharatiya, Philippe De Deurwaerdère.
  Handbook of Behavioral Neuroscience. 2020-01-01. : 197-215.
  10.1016/B978-0-444-64125-0.00010-4
• L-DOPA in parkinson’s disease: Looking at the “false” neurotransmitters and their meaning
  Chagraoui, Boulain, Juvin, Anouar, Barrière, Deurwaerdère.
  IJMS. 2019-12-31. 21(1) : 294.
  10.3390/ijms21010294
• Early neurochemical modifications of monoaminergic systems in the R6/1 mouse model of Huntington’s disease
  Emilie Puginier, Rahul Bharatiya, Abdeslam Chagraoui, Julien Manem, Yoon H. Cho, Maurice Garret, Philippe De Deurwaerdère.
  Neurochemistry International. 2019-09-01. 128 : 186-195.
  10.1016/j.neuint.2019.05.001
• Reciprocal interaction between monoaminergic systems and the pedunculopontine nucleus: Implication in the mechanism of L-DOPA
  Giuseppe Di Giovanni, Abdeslam Chagraoui, Emilie Puginier, Salvatore Galati, Philippe De Deurwaerdère.
  Neurobiology of Disease. 2019-08-01. 128 : 9-18.
  10.1016/j.nbd.2018.08.014
• Effect of the 5-HT2C Receptor Agonist WAY-163909 on Serotonin and Dopamine Metabolism across the Rat Brain: A Quantitative and Qualitative Neurochemical Study
  Sara Whitestone, Philippe De Deurwaerdère, Lynn Baassiri, Julien Manem, Youssef Anouar, Giuseppe Di Giovanni, Rahul Bharatiya, Abdeslam Chagraoui.
  IJMS. 2019-06-14. 20(12) : 2925.
  10.3390/ijms20122925
• Neurochemical impact of the 5-HT 2C receptor agonist WAY-163909 on monoamine tissue content in the rat brain
  Abdeslam Chagraoui, Sara Whitestone, Lynn Baassiri, Julien Manem, Giuseppe Di Giovanni, Philippe De Deurwaerdère.
  Neurochemistry International. 2019-03-01. 124 : 245-255.
  10.1016/j.neuint.2019.01.019
• Exogenous LRRK2G2019S induces parkinsonian-like pathology in a nonhuman primate
  Nadine Mestre-Francés, Nicolas Serratrice, Aurélie Gennetier, Gina Devau, Sandra Cobo, Stéphanie G. Trouche, Pascaline Fontès, Charleine Zussy, Philippe De Deurwaerdere, Sara Salinas, Franck J.D. Mennechet, Julien Dusonchet, Bernard L. Schneider, Isabella Saggio, Vasiliki Kalatzis, M. Rosario Luquin-Piudo, Jean-Michel Verdier, Eric J. Kremer.
  JCI Insight. 2018-07-25. 3(14)
  10.1172/jci.insight.98202
• Alteration of nociceptive integration in the spinal cord of a rat model of Parkinson’s disease
  Keri-Ann Charles, Frédéric Naudet, Rabia Bouali-Benazzouz, Marc Landry, Philippe De Deurwaerdère, Pascal Fossat, Abdelhamid Benazzouz.
  Mov Disord.. 2018-05-18. 33(6) : 1010-1015.
  10.1002/mds.27377
• Lead-induced atypical Parkinsonism in rats: Behavioral, electrophysiological, and neurochemical evidence for a role of noradrenaline depletion
  Mariam Sabbar, Claire Delaville, Philippe De Deurwaerdère, Nouria Lakhdar-Ghazal, Abdelhamid Benazzouz.
  Front. Neurosci.. 2018-03-19. 12
  10.3389/fnins.2018.00173
• Inter-individual differences in the impulsive/compulsive dimension: deciphering related dopaminergic and serotonergic metabolisms at rest
  Françoise Dellu-Hagedorn, Marion Rivalan, Aurélie Fitoussi, Philippe De Deurwaerdère.
  Phil. Trans. R. Soc. B. 2018-02-26. 373(1744) : 20170154.
  10.1098/rstb.2017.0154
• Preferential modulation of the lateral habenula activity by serotonin-2A rather than -2C receptors: Electrophysiological and neuroanatomical evidence
  Francis Delicata, Cristiano Bombardi, Massimo Pierucci, Roberto Di Maio, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  CNS Neurosci Ther. 2018-02-25. 24(8) : 721-733.
  10.1111/cns.12830
• Preferential modulation of the lateral habenula activity by serotonin‐2A rather than ‐2C receptors: Electrophysiological and neuroanatomical evidence
  Francis Delicata, Cristiano Bombardi, Massimo Pierucci, Roberto Di Maio, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  CNS Neurosci Ther. 2018-02-25. 24(8) : 721-733.
  10.1111/cns.12830
• 5-HT2A receptors in the basal ganglia
  Cristina Miguelez, Teresa Morera-Herreras, Philippe De Deurwaerdère.
  5-HT2A Receptors in the Central Nervous System. 2018-01-01. : 273-310.
  10.1007/978-3-319-70474-6_12
• Pharmacological analysis in favour of a physiological role for the constitutive activity of 5-HT2A receptors in learning
  Philippe De Deurwaerdère, Guillaume Drutel, Giuseppe Di Giovanni.
  5-HT2A Receptors in the Central Nervous System. 2018-01-01. : 3-29.
  10.1007/978-3-319-70474-6_1
• Role of serotonin2A (5-HT2A) receptors in epilepsy
  Vincenzo Crunelli, Marcello Venzi, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  5-HT2A Receptors in the Central Nervous System. 2018-01-01. : 375-394.
  10.1007/978-3-319-70474-6_16
• Purposeless oral activity induced by meta-chlorophenylpiperazine (m-CPP): Undefined tic-like behaviors?
  Deborah S. Kreiss, Philippe De Deurwaerdère.
  Journal of Neuroscience Methods. 2017-12-01. 292 : 30-36.
  10.1016/j.jneumeth.2017.05.007
• Does the Serotonin2C receptor segregate circuits of the basal ganglia responding to cingulate cortex stimulation?
  Mélanie Lagière, Marion Bosc, Sara Whitestone, Julien Manem, Hasna Elboukhari, Abdelhamid Benazzouz, Giuseppe Di Giovanni, Philippe De Deurwaerdère.
  CNS Neurosci Ther. 2017-11-15. 24(8) : 741-744.
  10.1111/cns.12777
• Impairment of serotonergic transmission by the antiparkinsonian drug L-DOPA: Mechanisms and clinical implications
  Cristina Miguelez, Abdelhamid Benazzouz, Luisa Ugedo, Philippe De Deurwaerdère.
  Front. Cell. Neurosci.. 2017-09-12. 11
  10.3389/fncel.2017.00274
• Serotonergic modulation of the activity of mesencephalic dopaminergic systems: Therapeutic implications
  Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  Progress in Neurobiology. 2017-04-01. 151 : 175-236.
  10.1016/j.pneurobio.2016.03.004
• Expanding the repertoire of L-DOPA’s actions: A comprehensive review of its functional neurochemistry
  Philippe De Deurwaerdère, Giuseppe Di Giovanni, Mark J. Millan.
  Progress in Neurobiology. 2017-04-01. 151 : 57-100.
  10.1016/j.pneurobio.2016.07.002
• Neurobiology and neuropharmacology of monoaminergic systems
  Philippe De Deurwaerdère, Rona R. Ramsay, Giuseppe Di Giovanni.
  Progress in Neurobiology. 2017-04-01. 151 : 1-3.
  10.1016/j.pneurobio.2017.02.001
• Correlative analysis of dopaminergic and serotonergic metabolism across the brain to study monoaminergic function and interaction
  Françoise Dellu-Hagedorn, Aurélie Fitoussi, Philippe De Deurwaerdère.
  Journal of Neuroscience Methods. 2017-03-01. 280 : 54-63.
  10.1016/j.jneumeth.2017.01.020
• Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine
  Philippe De Deurwaerdère, Claudia Binda, Rémi Corne, Cosima Leone, Aurora Valeri, Massimo Valoti, Rona R. Ramsay, Yagamare Fall, José Marco-Contelles.
  ACS Chem. Neurosci.. 2016-12-30. 8(5) : 1026-1035.
  10.1021/acschemneuro.6b00377
• Cortico-subthalamic inputs from the motor, limbic, and associative areas in normal and dopamine-depleted rats are not fully segregated
  Marcus L. F. Janssen, Yasin Temel, Claire Delaville, Daphne G. M. Zwartjes, Tjitske Heida, Philippe De Deurwaerdère, Veerle Visser-Vandewalle, Abdelhamid Benazzouz.
  Brain Struct Funct. 2016-12-24. 222(6) : 2473-2485.
  10.1007/s00429-016-1351-5
• Monoaminergic and histaminergic strategies and treatments in brain diseases
  Giuseppe Di Giovanni, Dubravka Svob Strac, Montse Sole, Mercedes Unzeta, Keith F. Tipton, Dorotea Mück-Šeler, Irene Bolea, Laura Della Corte, Matea Nikolac Perkovic, Nela Pivac, Ilse J. Smolders, Anna Stasiak, Wieslawa A. Fogel, Philippe De Deurwaerdère.
  Front. Neurosci.. 2016-11-24. 10
  10.3389/fnins.2016.00541
• Monoaminergic mechanisms in epilepsy may offer innovative therapeutic opportunity for monoaminergic multi-target drugs
  Dubravka Svob Strac, Nela Pivac, Ilse J. Smolders, Wieslawa A. Fogel, Philippe De Deurwaerdere, Giuseppe Di Giovanni.
  Front. Neurosci.. 2016-11-10. 10
  10.3389/fnins.2016.00492
• L-DOPA elicits non-vesicular releases of serotonin and dopamine in hemiparkinsonian rats in vivo
  Cristina Miguelez, Sylvia Navailles, Claire Delaville, Loïse Marquis, Mélanie Lagière, Abdelhamid Benazzouz, Luisa Ugedo, Philippe De Deurwaerdère.
  European Neuropsychopharmacology. 2016-08-01. 26(8) : 1297-1309.
  10.1016/j.euroneuro.2016.05.004
• Updating neuropathology and neuropharmacology of monoaminergic systems
  Rona R Ramsay, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  British Journal of Pharmacology. 2016-06-14. 173(13) : 2065-2068.
  10.1111/bph.13508
• The acute and long-term L-DOPA effects are independent from changes in the activity of dorsal raphe serotonergic neurons in 6-OHDA lesioned rats
  C Miguelez, S Navailles, P De Deurwaerdère, L Ugedo.
  British Journal of Pharmacology. 2016-03-08. 173(13) : 2135-2146.
  10.1111/bph.13447
• New therapeutic opportunities for 5-HT2C receptor ligands in neuropsychiatric disorders.
  Giuseppe Di Giovanni, Philippe De Deurwaerdère.
  Pharmacology & Therapeutics. 2016-01-01. 157 : 125-162.
  10.1016/j.pharmthera.2015.11.009
• Cariprazine: New dopamine biased agonist for neuropsychiatry disorders
  B. SaiKiran.
  Drugs Today. 2016-01-01. 52(2) : 97.
  10.1358/dot.2016.52.2.2461868
• The impact of combined administration of paraquat and maneb on motor and non-motor functions in the rat
  A. Tinakoua, S. Bouabid, E. Faggiani, P. De Deurwaerdère, N. Lakhdar-Ghazal, A. Benazzouz.
  Neuroscience. 2015-12-01. 311 : 118-129.
  10.1016/j.neuroscience.2015.10.021
• Monoamine content during the reproductive cycle of Perna perna depends on site of origin on the Atlantic Coast of Morocco.
  Mounia S. Klouche, Philippe De Deurwaerdère, Françoise Dellu-Hagedorn, Nouria Lakhdar-Ghazal, Soumaya Benomar.
  Sci Rep. 2015-09-09. 5(1)
  10.1038/srep13715
• Monoamine content during the reproductive cycle of Perna perna depends on site of origin on the Atlantic Coast of Morocco
  Mounia S. Klouche, Philippe De Deurwaerdère, Françoise Dellu-Hagedorn, Nouria Lakhdar-Ghazal, Soumaya Benomar.
  Sci Rep. 2015-09-09. 5(1)
  10.1038/srep13715
• The 5-HT4 Agonist Prucalopride Stimulates L-DOPA-Induced Dopamine Release in Restricted Brain Regions of the Hemiparkinsonian Rat In Vivo.
  Sylvia Navailles, Giuseppe Di Giovanni, Philippe De Deurwaerdère.
  CNS Neurosci Ther. 2015-07-24. 21(9) : 745-747.
  10.1111/cns.12436
• The 5-HT<inf>4</inf> Agonist Prucalopride Stimulates L-DOPA-Induced Dopamine Release in Restricted Brain Regions of the Hemiparkinsonian Rat In Vivo
  Sylvia Navailles, Giuseppe Di Giovanni, Philippe De Deurwaerdère.
  CNS Neurosci Ther. 2015-07-24. 21(9) : 745-747.
  10.1111/cns.12436
• Serotonin, but not dopamine, controls the stress response and anxiety-like behavior in the crayfish Procambarus clarkii.
  P. Fossat, J. Bacque-Cazenave, P. De Deurwaerdere, D. Cattaert, J.-P. Delbecque.
  Journal of Experimental Biology. 2015-07-02. 218(17) : 2745-2752.
  10.1242/jeb.120550
• Blood withdrawal affects iron store dynamics in primates with consequences on monoaminergic system function
  C. Hyacinthe, P. De Deurwaerdere, T. Thiollier, Q. Li, E. Bezard, I. Ghorayeb.
  Neuroscience. 2015-04-01. 290 : 621-635.
  10.1016/j.neuroscience.2015.01.057
• NMDA receptor antagonism potentiates the L-DOPA-induced extracellular dopamine release in the subthalamic nucleus of hemi-parkinson rats.
  Anissa El Arfani, Eduard Bentea, Najat Aourz, Ben Ampe, Philippe De Deurwaerdère, Ann Van Eeckhaut, Ann Massie, Sophie Sarre, Ilse Smolders, Yvette Michotte.
  Neuropharmacology. 2014-10-01. 85 : 198-205.
  10.1016/j.neuropharm.2014.05.024
• Role(s) of the 5-HT2C receptor in the development of maximal dentate activation in the hippocampus of anesthetized rats (vol 20, pg 651, 2014)
  .
  CNS Neurosci Ther. 2014-09-26. 20(10) : 950-950.
  10.1111/CNS.12324
• Role(s) of the 5-HT2C receptor in the development of maximal dentate activation in the hippocampus of anesthetized rats.
  Gergely Orban, Cristiano Bombardi, Antonella Marino Gammazza, Roberto Colangeli, Massimo Pierucci, Cristoforo Pomara, Mauro Pessia, Fabio Bucchieri, Benigno Arcangelo, Ilse Smolders, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  CNS Neurosci Ther. 2014-06-17. 20(7) : 651-661.
  10.1111/cns.12285
• Role(s) of the 5-HT2C receptor in the development of maximal dentate activation in the hippocampus of anesthetized rats
  Gergely Orban, Cristiano Bombardi, Antonella Marino Gammazza, Roberto Colangeli, Massimo Pierucci, Cristoforo Pomara, Mauro Pessia, Fabio Bucchieri, Benigno Arcangelo, Ilse Smolders, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  CNS Neurosci Ther. 2014-06-17. 20(7) : 651-661.
  10.1111/cns.12285
• Anxiety-like behavior in crayfish is controlled by serotonin
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  Science. 2014-06-12. 344(6189) : 1293-1297.
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• Manganese-induced atypical parkinsonism is associated with altered Basal Ganglia activity and changes in tissue levels of monoamines in the rat.
  Safa Bouabid, Claire Delaville, Philippe De Deurwaerdère, Nouria Lakhdar-Ghazal, Abdelhamid Benazzouz.
  PLoS ONE. 2014-06-04. 9(6) : e98952.
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• N-(furan-2-ylmethyl)-N-methylprop-2-yn-1-amine (F2MPA): A potential cognitive enhancer with MAO inhibitor properties.
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• N-(furan-2-ylmethyl)-N-methylprop-2-yn-1-amine (F2MPA): A potential cognitive enhancer with MAO inhibitor properties
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• Noradrenergic terminals regulate L-DOPA-derived dopamine extracellular levels in a region-dependent manner in Parkinsonian rats.
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  CNS Neurosci Ther. 2014-04-28. 20(7) : 671-678.
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• Noradrenergic terminals regulate l-DOPA-derived dopamine extracellular levels in a region-dependent manner in Parkinsonian rats
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  CNS Neurosci Ther. 2014-04-28. 20(7) : 671-678.
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• Predicting dopaminergic effects of L-DOPA in the treatment for Parkinson’s disease.
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  CNS Neurosci Ther. 2014-03-15. 20(7) : 699-701.
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• Predicting dopaminergic effects of L-DOPA in the treatment for Parkinson’s disease
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  CNS Neurosci Ther. 2014-03-15. 20(7) : 699-701.
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• L-DOPA and the Brain Pattern of Dopamine Extracellular Levels: A New Deal Imposed by Serotonergic and Noradrenergic Fibres
  Philippe De Deurwaerdère, Sylvia Navailles, Léa Milan.
  Catecholamine Research in the 21st Century. 2014-01-01. : 251.
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• Role of central serotonin receptors in nicotine addiction
  Massimo Pierucci, Stephanie Chambers, Lucy Partridge, Philippe De Deurwaerdère, Giuseppe Di Giovanni.
  Nicotinic Receptors. 2014-01-01. : 279-305.
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• Monoamines tissue content analysis reveals restricted and site-specific correlations in brain regions involved in cognition
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  Neuroscience. 2013-12-01. 255 : 233-245.
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• Serotonin2c receptor constitutive activity: in vivo direct and indirect evidence and functional significance.
  Sylvia Navailles, Mélanie Lagière, Martin Guthrie, Philippe Deurwaerdère.
  CNSAMC. 2013-10-01. 13(2) : 98-107.
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• A tobacco extract containing alkaloids induces distinct effects compared to pure nicotine on dopamine release in the rat.
  Hanane Khalki, Sylvia Navailles, Camille L. Piron, Philippe De Deurwaerdère.
  Neuroscience Letters. 2013-06-01. 544 : 85-88.
  10.1016/j.neulet.2013.03.047
• Role of 5-HT2C receptors in the enhancement of c-Fos expression induced by a 5-HT2B/2C inverse agonist and 5-HT2 agonists in the rat basal ganglia
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  Exp Brain Res. 2013-05-17. 230(4) : 525-535.
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• Multiple controls exerted by 5-HT2C receptors upon basal ganglia function: From physiology to pathophysiology
  P. De Deurwaerdère, M. Lagière, M. Bosc, S. Navailles.
  Exp Brain Res. 2013-04-25. 230(4) : 477-511.
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• Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: Distinct effects of agonists and inverse agonists in a rat model of Parkinson’s disease
  Sylvia Navailles, Mélanie Lagière, Audrey Roumegous, Marina Polito, Méric B. Boujema, Martine Cador, John Dunlop, Marie-Françoise Chesselet, Mark J. Millan, Philippe De Deurwaerdère.
  International Journal of Neuropsychopharmacology. 2013-04-01. 16(3) : 593-606.
  10.1017/S1461145712000417
• Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson’s disease.
  Sylvia Navailles, Mélanie Lagière, Audrey Roumegous, Marina Polito, Méric B. Boujema, Martine Cador, John Dunlop, Marie-Françoise Chesselet, Mark J. Millan, Philippe De Deurwaerdère.
  International Journal of Neuropsychopharmacology. 2013-04-01. 16(3) : 593-606.
  10.1017/S1461145712000417
• Intrapallidal administration of 6-hydroxydopamine mimics in large part the electrophysiological and behavioral consequences of major dopamine depletion in the rat
  P.M. Abedi, C. Delaville, P. De Deurwaerdère, W. Benjelloun, A. Benazzouz.
  Neuroscience. 2013-04-01. 236 : 289-297.
  10.1016/j.neuroscience.2013.01.043
• The enhanced oral response to the 5-HT2 agonist Ro 60-0175 in parkinsonian rats involves the entopeduncular nucleus: Electrophysiological correlates
  M. Lagière, S. Navailles, L. Mignon, A. Roumegous, M.-F. Chesselet, P. De Deurwaerdère.
  Exp Brain Res. 2013-03-28. 230(4) : 513-524.
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• Serotonin2C Receptors and the Motor Control of Oral Activity.
  Melanie Lagiere, Sylvia Navailles, Marion Bosc, Martin Guthrie, Philippe Deurwaerdere.
  CN. 2013-03-01. 11(2) : 160-170.
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• Catecholamine/Serotonin interactions: systems thinking for brain function and disease.
  Julie G. Hensler, Francesc Artigas, Analía Bortolozzi, Lynette C. Daws, Philippe De Deurwaerdère, Léa Milan, Sylvia Navailles, Wouter Koek.
  A New Era of Catecholamines in the Laboratory and Clinic. 2013-01-01. : 167-197.
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• What can we expect from the serotonergic side of l-DOPA? | Que pouvons-nous attendre de la composante sérotoninergique de la l-DOPA ?
  P. De Deurwaerdère, S. Navailles.
  Revue Neurologique. 2012-12-01. 168(12) : 927-938.
  10.1016/j.neurol.2012.01.585
• Lead intoxication induces noradrenaline depletion, motor nonmotor disabilities, and changes in the firing pattern of subthalamic nucleus neurons
  M. Sabbar, C. Delaville, P. De Deurwaerdère, A. Benazzouz, N. Lakhdar-Ghazal.
  Neuroscience. 2012-05-01. 210 : 375-383.
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• Emerging dysfunctions consequent to combined monoaminergic depletions in parkinsonism
  Claire Delaville, Jonathan Chetrit, Khaled Abdallah, Stéphanie Morin, Laura Cardoit, Philippe De Deurwaerdère, Abdelhamid Benazzouz.
  Neurobiology of Disease. 2012-02-01. 45(2) : 763-773.
  10.1016/j.nbd.2011.10.023
• Contribution of serotonergic transmission to the motor and cognitive effects of high-frequency stimulation of the subthalamic nucleus or levodopa in Parkinson’s disease
  Sylvia Navailles, Philippe De Deurwaerdère.
  Mol Neurobiol. 2012-01-06. 45(1) : 173-185.
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• L-DOPA and serotonergic neurons: functional implication and therapeutic perspectives in Parkinson’s disease.
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  CNSAMC. 2011-12-01. 11(4) : 305-320.
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• Chronic L-DOPA therapy alters central serotonergic function and L-DOPA-induced dopamine release in a region-dependent manner in a rat model of Parkinson’s disease
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  Neurobiology of Disease. 2011-02-01. 41(2) : 585-590.
  10.1016/j.nbd.2010.11.007
• Noradrenaline and Parkinson’s disease
  Claire Delaville, Philippe De Deurwaerdère, Abdelhamid Benazzouz.
  Front. Syst. Neurosci.. 2011-01-01. 5
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• Presynaptic control of serotonin on striatal dopamine function
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  Psychopharmacology. 2010-10-16. 213(2-3) : 213-242.
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• Serotonergic neurons mediate ectopic release of dopamine induced by l-DOPA in a rat model of Parkinson’s disease
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  Neurobiology of Disease. 2010-04-01. 38(1) : 136-143.
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• High-frequency stimulation of the subthalamic nucleus and L-3,4-dihydroxyphenylalanine inhibit in vivo serotonin release in the prefrontal cortex and hippocampus in a rat model of Parkinson’s disease
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  Journal of Neuroscience. 2010-02-10. 30(6) : 2356-2364.
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• Clozapine and haloperidol differentially alter the constitutive activity of central serotonin2C receptors in vivo
  Sylvia Navailles, Philippe De Deurwaerdère, Umberto Spampinato.
  Biological Psychiatry. 2006-03-01. 59(6) : 568-575.
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• Clozapine and haloperidol differentially alter the constitutive activity of central serotonin2C receptors in vivo
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  Biological Psychiatry. 2006-03-01. 59(6) : 568-575.
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• Regionally and functionally distinct serotonin3 receptors control in vivo dopamine outflow in the rat nucleus accumbens
  Philippe De Deurwaerdere, Delphine Moison, Sylvia Navailles, Gregory Porras, Umberto Spampinato.
  J Neurochem. 2005-07-01. 94(1) : 140-149.
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• Constitutive Activity of the Serotonin2C Receptor Inhibits In Vivo Dopamine Release in the Rat Striatum and Nucleus Accumbens
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• Intrastriatal administration of sigma ligands inhibits basal dopamine release in vivo
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• In Vivo Evidence that 5-HT2C Receptor Antagonist but not Agonist Modulates Cocaine-Induced Dopamine Outflow in the Rat Nucleus Accumbens and Striatum
  Sylvia Navailles, Philippe De Deurwaerdère, Grégory Porras, Umberto Spampinato.
  Neuropsychopharmacol. 2003-10-15. 29(2) : 319-326.
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• In Vivo Evidence that 5-HT2C Receptor Antagonist but not Agonist Modulates Cocaine-Induced Dopamine Outflow in the Rat Nucleus Accumbens and Striatum
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  Neuropsychopharmacol. 2003-10-15. 29(2) : 319-326.
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• Selective serotonin reuptake inhibitors enhance cocaine-induced locomotor activity and dopamine release in the nucleus accumbens
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  Neuropharmacology. 2003-03-01. 44(3) : 342-353.
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• Conditional involvement of striatal serotonin3 receptors in the control of in vivo dopamine outflow in the rat striatum
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  European Journal of Neuroscience. 2003-02-01. 17(4) : 771-781.
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• Central serotonin4 receptors selectively regulate the impulse-dependent exocytosis of dopamine in the rat striatum: In vivo studies with morphine, amphetamine and cocaine
  Grégory Porras, Vincenzo Di Matteo, Philippe De Deurwaerdère, Ennio Esposito, Umberto Spampinato.
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• Central serotonin4 receptors selectively regulate the impulse-dependent exocytosis of dopamine in the rat striatum: In vivo studies with morphine, amphetamine and cocaine
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• Central 5-HT4 receptors and dopamine-dependent motor behaviors: Searching for a functional role
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  Pharmacology Biochemistry and Behavior. 2002-04-01. 71(4) : 627-633.
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• Central 5-HT4 receptors and dopamine-dependent motor behaviors: Searching for a functional role
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• 5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum
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• 5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum
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• D-amphetamine-induced behavioral sensitization: Effect of lesioning dopaminergic terminals in the medial prefrontal cortex, the amygdala and the entorhinal cortex
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• Role of serotonin(2A) and serotonin(2B/2C) receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation
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• The nigrostriatal dopamine system: A neglected target for 5-HT2C receptors (1)
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• Neurochemical and electrophysiological evidence that 5-HT4 receptors exert a state-dependent facilitatory control in vivo on nigrostriatal, but not mesoaccumbal, dopaminergic function
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  European Journal of Neuroscience. 2001-03-01. 13(5) : 889-898.
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• Endogenous serotonin enhances the release of dopamine in the striatum only when nigro-striatal dopaminergic transmission is activated
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• The effect of serotonergic agents on haloperidol-induced striatal dopamine release in vivo: Opposite role of 5-HT(2A) and 5-HT(2C) receptor subtypes and significance of the haloperidol dose used
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• Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: A combined in vivo electrophysiological and microdialysis study
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  Neuroscience. 1999-06-01. 91(2) : 587-597.
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• 8-OH-DPAT, a 5-HT(1a) agonist and ritanserin, a 5-HT(2A/C) antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release
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  Psychopharmacology. 1997-05-15. 131(1) : 57-63.
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• Evidence for 5-HT4 receptor subtype involvement in the enhancement of striatal dopamine release induced by serotonin: a microdialysis study in the halothane-anesthetized rat
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