François Georges

Publications

• A population of Insula neurons encodes for social preference only after acute social isolation in mice
  Christelle Glangetas, Adriane Guillaumin, Elodie Ladevèze, Anaelle Braine, Manon Gauthier, Léa Bonamy, Evelyne Doudnikoff, Thibault Dhellemmes, Marc Landry, Erwan Bézard, Stephanie Caille, Anne Taupignon, Jérôme Baufreton, François Georges.
  Nat Commun. 2024-08-21. 15(1)
  10.1038/s41467-024-51389-4
• Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure
  Roman Walle, Anna Petitbon, Giulia R. Fois, Christophe Varin, Enrica Montalban, Lola Hardt, Andrea Contini, Maria Florencia Angelo, Mylène Potier, Rodrigue Ortole, Asma Oummadi, Véronique De Smedt-Peyrusse, Roger A. Adan, Bruno Giros, Francis Chaouloff, Guillaume Ferreira, Alban de Kerchove d’Exaerde, Fabien Ducrocq, François Georges, Pierre Trifilieff.
  Nat Commun. 2024-03-21. 15(1)
  10.1038/s41467-024-46874-9
• Emotion in action: When emotions meet motor circuits
  Anaelle Braine, François Georges.
  Neuroscience & Biobehavioral Reviews. 2023-12-01. 155 : 105475.
  10.1016/j.neubiorev.2023.105475
• A role for the subthalamic nucleus in aversive learning
  Gian Pietro Serra, Adriane Guillaumin, Bianca Vlcek, Lorena Delgado-Zabalza, Alessia Ricci, Eleonora Rubino, Sylvie Dumas, Jérôme Baufreton, François Georges, Åsa Wallén-Mackenzie.
  Cell Reports. 2023-11-01. 42(11) : 113328.
  10.1016/j.celrep.2023.113328
• Encoding social preference by interhemispheric neurons in the Insula
  Christelle Glangetas, Elodie Ladevèze, Adriane Guillaumin, Manon Gauthier, Evelyne Doudnikoff, Erwan Bézard, Anne Taupignon, Jérôme Baufreton, François Georges.
  . 2022-12-15.
  10.1101/2022.12.15.520538
• A non-canonical GABAergic pathway to the VTA promotes unconditioned freezing
  Loïc Broussot, Thomas Contesse, Renan Costa-Campos, Christelle Glangetas, Léa Royon, Hugo Fofo, Thomas Lorivel, François Georges, Sebastian P. Fernandez, Jacques Barik.
  Mol Psychiatry. 2022-09-20. 27(12) : 4905-4917.
  10.1038/s41380-022-01765-7
• Locus coeruleus activation during environmental novelty gates cocaine-induced long-term hyperactivity of dopamine neurons
  Giulia R. Fois, Karl Y. Bosque-Cordero, Rafael Vazquez-Torres, Cristina Miliano, Xavier Nogues, Carlos A. Jimenez-Rivera, Stéphanie Caille, François Georges.
  iScience. 2022-04-01. 25(4) : 104154.
  10.1016/j.isci.2022.104154
• Ih blockade reduces cocaine-induced firing patterns of putative dopaminergic neurons of the ventral tegmental area in the anesthetized rat
  Karl Y. Bosque-Cordero, Rafael Vazquez-Torres, Cristhian Calo-Guadalupe, Daisy Consuegra-Garcia, Giulia R. Fois, François Georges, Carlos A. Jimenez-Rivera.
  Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2022-01-01. 112 : 110431.
  10.1016/j.pnpbp.2021.110431
• Exercise craving potentiates excitatory inputs to ventral tegmental area dopaminergic neurons
  Maria‐Carmen Medrano, Imane Hurel, Emma Mesguich, Bastien Redon, Christopher Stevens, François Georges, Miriam Melis, Giovanni Marsicano, Francis Chaouloff.
  Addiction Biology. 2020-10-05.
  10.1111/adb.12967
• Aversion encoded in the subthalamic nucleus
  Gian Pietro Serra, Adriane Guillaumin, Jérome Baufreton, François Georges, Åsa Wallén-Mackenzie.
  . 2020-07-10.
  10.1101/2020.07.09.195610
• Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice
  Eléonore Bertin, Thomas Deluc, Kjara S. Pilch, Audrey Martinez, Johan-Till Pougnet, Evelyne Doudnikoff, Anne-Emilie Allain, Philine Bergmann, Marion Russeau, Estelle Toulmé, Erwan Bezard, Friedrich Koch-Nolte, Philippe Séguéla, Sabine Lévi, Bruno Bontempi, François Georges, Sandrine S. Bertrand, Olivier Nicole, Eric Boué-Grabot.
  Mol Psychiatry. 2020-01-08.
  10.1038/s41380-019-0641-8
• The ergogenic impact of the glucocorticoid prednisolone does not translate into increased running motivation in mice
  Bastien Redon, Claire Violleau, François Georges, Giovanni Marsicano, Francis Chaouloff.
  Psychoneuroendocrinology. 2020-01-01. 111 : 104489.
  10.1016/j.psyneuen.2019.104489
• The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors.
  Carolina Muguruza, Bastien Redon, Giulia R. Fois, Imane Hurel, Amandine Scocard, Claire Nguyen, Christopher Stevens, Edgar Soria-Gomez, Marjorie Varilh, Astrid Cannich, Justine Daniault, Arnau Busquets-Garcia, Teresa Pelliccia, Stéphanie Caillé, François Georges, Giovanni Marsicano, Francis Chaouloff.
  JCI Insight. 2019-03-07. 4(5)
  10.1172/jci.insight.126190
• Species-specific diversity in the anatomical and physiological organisation of the BNST-VTA pathway.
  Jennifer Kaufling, Delphine Girard, Marlène Maitre, Thierry Leste-Lasserre, François Georges.
  Eur J Neurosci. 2017-03-28. 45(9) : 1230-1240.
  10.1111/ejn.13554
• NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis.
  Christelle Glangetas, Léma Massi, Giulia R. Fois, Marion Jalabert, Delphine Girard, Marco Diana, Keisuke Yonehara, Botond Roska, Chun Xu, Andreas Lüthi, Stéphanie Caille, François Georges.
  Nat Comms. 2017-02-20. 8 : 14456.
  10.1038/ncomms14456
• Cocaine Exposure Enhances the Activity of Ventral Tegmental Area Dopamine Neurons via Calcium-Impermeable NMDARs.
  Meaghan Creed, Jennifer Kaufling, Giulia R. Fois, Marion Jalabert, Tifei Yuan, Christian Lüscher, Francois Georges, Camilla Bellone.
  J. Neurosci.. 2016-10-19. 36(42) : 10759-10768.
  10.1523/jneurosci.1703-16.2016
• Chronic morphine exposure and spontaneous withdrawal are associated with modifications of dopamine receptor and neuropeptide gene expression in the rat striatum.
  Georges F1, Stinus L, Bloch B, Le Moine C..
  Eur J Neurosci.. 1999-02-01. 11(2) : 481-90.
  10.1046/j.1460-9568.1999.00462.x
• Opioid receptor gene expression in the rat brain during ontogeny, with special reference to the mesostriatal system: an in situ hybridization study.
  Georges F1, Normand E, Bloch B, Le Moine C..
  Brain Res Dev Brain Res.. 1998-08-08. 109(2) : 187-99.
  10.1016/s0165-3806(98)00082-0
• Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons.
  .
  J Neurosci.. 2016-10-17. 22(12) : 5173-87.
  
• SHANK3 controls maturation of social reward circuits in the VTA.
  Sebastiano Bariselli, Stamatina Tzanoulinou, Christelle Glangetas, Clément Prévost-Solié, Luca Pucci, Joanna Viguié, Paola Bezzi, Eoin C O'Connor, François Georges, Christian Lüscher, Camilla Bellone.
  Nat Neurosci. 2016-06-06. 19(7) : 926-934.
  10.1038/nn.4319
• Temporal Memory and Its Enhancement by Estradiol Requires Surface Dynamics of Hippocampal CA1 N-Methyl-D-Aspartate Receptors.
  Mylène Potier, François Georges, Laurent Brayda-Bruno, Laurent Ladépêche, Valérie Lamothe, Alice Shaam Al Abed, Laurent Groc, Aline Marighetto.
  Biological Psychiatry. 2016-05-01. 79(9) : 735-745.
  10.1016/j.biopsych.2015.07.017
• Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine.
  Christelle Glangetas, Giulia R. Fois, Marion Jalabert, Salvatore Lecca, Kristina Valentinova, Frank J. Meye, Marco Diana, Philippe Faure, Manuel Mameli, Stéphanie Caille, François Georges.
  Cell Reports. 2015-12-01. 13(10) : 2287-2296.
  10.1016/j.celrep.2015.10.076
• Habenular CB1 Receptors Control the Expression of Aversive Memories.
  Edgar Soria-Gómez, Arnau Busquets-Garcia, Fei Hu, Amine Mehidi, Astrid Cannich, Liza Roux, Ines Louit, Lucille Alonso, Theresa Wiesner, Francois Georges, Danièle Verrier, Peggy Vincent, Guillaume Ferreira, Minmin Luo, Giovanni Marsicano.
  Neuron. 2015-10-01. 88(2) : 306-313.
  10.1016/j.neuron.2015.08.035
• Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.
  Mathieu Bourdenx, Sandra Dovero, Michel Engeln, Simone Bido, Matthieu F. Bastide, Nathalie Dutheil, Isabel Vollenweider, Laetitia Baud, Camille Piron, Virginie Grouthier, Thomas Boraud, Grégory Porras, Qin Li, Veerle Baekelandt, Dieter Scheller, Anne Michel, Pierre-Olivier Fernagut, François Georges, Grégoire Courtine, Erwan Bezard, Benjamin Dehay.
  acta neuropathol commun. 2015-07-25. 3(1)
  10.1186/s40478-015-0222-2
• Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula.
  Frank J Meye, Kristina Valentinova, Salvatore Lecca, Lucile Marion-Poll, Matthieu J Maroteaux, Stefano Musardo, Imane Moutkine, Fabrizio Gardoni, Richard L Huganir, François Georges, Manuel Mameli.
  Nat Neurosci. 2015-02-02. 18(3) : 376-378.
  10.1038/nn.3923
• The antero-posterior heterogeneity of the ventral tegmental area.
  M.J. Sanchez-Catalan, J. Kaufling, F. Georges, P. Veinante, M. Barrot.
  Neuroscience. 2014-12-01. 282 : 198-216.
  10.1016/j.neuroscience.2014.09.025
• Control of the nigrostriatal dopamine neuron activity and motor function by the tail of the ventral tegmental area.
  Romain Bourdy, María-José Sánchez-Catalán, Jennifer Kaufling, Judith J Balcita-Pedicino, Marie-José Freund-Mercier, Pierre Veinante, Susan R Sesack, François Georges, Michel Barrot.
  Neuropsychopharmacol. 2014-06-04. 39(12) : 2788-2798.
  10.1038/npp.2014.129
• Nicotine self-administration induces CB1-dependent LTP in the bed nucleus of the stria terminalis.
  A.-R. Reisiger, J. Kaufling, O. Manzoni, M. Cador, F. Georges, S. Caille.
  Journal of Neuroscience. 2014-03-19. 34(12) : 4285-4292.
  10.1523/jneurosci.3149-13.2014
• Stress switches cannabinoid type-1 (CB1) receptor-dependent plasticity from LTD to LTP in the bed nucleus of the stria terminalis.
  C. Glangetas, D. Girard, L. Groc, G. Marsicano, F. Chaouloff, F. Georges.
  Journal of Neuroscience. 2013-12-11. 33(50) : 19657-19663.
  10.1523/jneurosci.3175-13.2013
• D1 dopamine receptor-mediated LTP at GABA synapses encodes motivation to self-administer cocaine in rats.
  M. Krawczyk, X. Mason, J. DeBacker, R. Sharma, C. P. Normandeau, E. R. Hawken, C. Di Prospero, C. Chiang, A. Martinez, A. A. Jones, E. Doudnikoff, S. Caille, E. Bezard, F. Georges, E. C. Dumont.
  Journal of Neuroscience. 2013-07-17. 33(29) : 11960-11971.
  10.1523/jneurosci.1784-13.2013
• Ventral tegmental area cannabinoid type-1 receptors control voluntary exercise performance.
  Sarah Dubreucq, Audrey Durand, Isabelle Matias, Giovanni Bénard, Elodie Richard, Edgar Soria-Gomez, Christelle Glangetas, Laurent Groc, Aya Wadleigh, Federico Massa, Dusan Bartsch, Giovanni Marsicano, Francois Georges, Francis Chaouloff.
  Biological Psychiatry. 2013-05-01. 73(9) : 895-903.
  10.1016/j.biopsych.2012.10.025
• Braking dopamine systems: a new GABA master structure for mesolimbic and nigrostriatal functions.
  M. Barrot, S. R. Sesack, F. Georges, M. Pistis, S. Hong, T. C. Jhou.
  Journal of Neuroscience. 2012-10-10. 32(41) : 14094-14101.
  10.1523/jneurosci.3370-12.2012
• Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis.
  Lenka Mikasova, Pierre De Rossi, Delphine Bouchet, François Georges, Véronique Rogemond, Adrien Didelot, Claire Meissirel, Jérôme Honnorat, Laurent Groc.
  Brain. 2012-04-27. 135(5) : 1606-1621.
  10.1093/brain/aws092
• Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD.
  Jing Han, Philip Kesner, Mathilde Metna-Laurent, Tingting Duan, Lin Xu, Francois Georges, Muriel Koehl, Djoher Nora Abrous, Juan Mendizabal-Zubiaga, Pedro Grandes, Qingsong Liu, Guang Bai, Wei Wang, Lize Xiong, Wei Ren, Giovanni Marsicano, Xia Zhang.
  Cell. 2012-03-01. 148(5) : 1039-1050.
  10.1016/j.cell.2012.01.037
• Polymodal activation of the endocannabinoid system in the extended amygdala.
  Nagore Puente, Yihui Cui, Olivier Lassalle, Mathieu Lafourcade, François Georges, Laurent Venance, Pedro Grandes, Olivier J Manzoni.
  Nat Neurosci. 2011-11-06. 14(12) : 1542-1547.
  10.1038/nn.2974
• Neuronal circuits underlying acute morphine action on dopamine neurons.
  M. Jalabert, R. Bourdy, J. Courtin, P. Veinante, O. J. Manzoni, M. Barrot, F. Georges.
  Proceedings of the National Academy of Sciences. 2011-09-19. 108(39) : 16446-16450.
  10.1073/pnas.1105418108
• Double-dissociation of the catecholaminergic modulation of synaptic transmission in the oval bed nucleus of the stria terminalis.
  Michal Krawczyk, François Georges, Robyn Sharma, Xenos Mason, Amandine Berthet, Erwan Bézard, Éric C. Dumont.
  Journal of Neurophysiology. 2011-01-01. 105(1) : 145-153.
  10.1152/jn.00710.2010
• Localization and function of the cannabinoid CB1 receptor in the anterolateral bed nucleus of the stria terminalis.
  Nagore Puente, Izaskun Elezgarai, Mathieu Lafourcade, Leire Reguero, Giovanni Marsicano, François Georges, Olivier J. Manzoni, Pedro Grandes.
  PLoS ONE. 2010-01-25. 5(1) : e8869.
  10.1371/journal.pone.0008869
• Role of the bed nucleus of the stria terminalis in the control of ventral tegmental area dopamine neurons.
  Marion Jalabert, Gary Aston-Jones, Etienne Herzog, Olivier Manzoni, François Georges.
  Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2009-11-01. 33(8) : 1336-1346.
  10.1016/j.pnpbp.2009.07.010
• Voluntary nicotine consumption triggers in vivo potentiation of cortical excitatory drives to midbrain dopaminergic neurons.
  S. Caille, K. Guillem, M. Cador, O. Manzoni, F. Georges.
  Journal of Neuroscience. 2009-08-19. 29(33) : 10410-10415.
  10.1523/jneurosci.2950-09.2009
• Cannabinoid receptors in the bed nucleus of the stria terminalis control cortical excitation of midbrain dopamine cells in vivo.
  L. Massi, I. Elezgarai, N. Puente, L. Reguero, P. Grandes, O. J. Manzoni, F. Georges.
  Journal of Neuroscience. 2008-10-15. 28(42) : 10496-10508.
  10.1523/jneurosci.2291-08.2008
• Novel neurons in ventral tegmental area fire selectively during the active phase of the diurnal cycle.
  Alice H. Luo, François E. Georges, Gary S. Aston-Jones.
  European Journal of Neuroscience. 2008-01-18. 27(2) : 408-422.
  10.1111/j.1460-9568.2007.05985.x
• Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic nonhuman primates: a call for a reappraisal of the functional organization of the basal ganglia.
  Nadjar A, Brotchie JM, Guigoni C, Li Q, Zhou SB, Wang GJ, Ravenscroft P, Georges F, Crossman AR, Bezard E..
  Journal of Neuroscience. 2006-08-23. 26(34) : 8653-8661.
  10.1523/jneurosci.2582-06.2006
• No effect of morphine on ventral tegmental dopamine neurons during withdrawal
  F. Georges.
  Journal of Neuroscience. 2006-05-24. 26(21) : 5720-5726.
  10.1523/jneurosci.5032-05.2006
• Role of imidazoline receptors in the anti-aversive properties of clonidine during opiate withdrawal in rats
  F. Georges, S. Caillé, C. Vouillac, C. Le Moine, L. Stinus.
  European Journal of Neuroscience. 2005-10-01. 22(7) : 1812-1816.
  10.1111/j.1460-9568.2005.04356.x
• Mapping of c-fos gene expression in the brain during morphine dependence and precipitated withdrawal, and phenotypic identification of the striatal neurons involved
  François Georges, Luis Stinus, Catherine Le Moine.
  European Journal of Neuroscience. 2000-12-01. 12(12) : 4475-4486.
  10.1046/j.0953-816X.2000.01334.x
• Chronic morphine exposure and spontaneous withdrawal are associated with modifications of dopamine receptor and neuropeptide gene expression in the rat striatum
  François Georges, Luis Stinus, Bertrand Bloch, Catherine Le Moine.
  European Journal of Neuroscience. 1999-02-01. 11(2) : 481-490.
  10.1046/j.1460-9568.1999.00462.x
• Opioid receptor gene expression in the rat brain during ontogeny, with special reference to the mesostriatal system: an in situ hybridization study
  François Georges, Elisabeth Normand, Bertrand Bloch, Catherine Le Moine.
  Developmental Brain Research. 1998-08-01. 109(2) : 187-199.
  10.1016/s0165-3806(98)00082-0