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Seminar – David Robbe

mercredi 15 mai / 11:00

Venue: Centre Broca


David Robbe - © copyright Bernier/Gwendoline/2019.
David Robbe – © copyright Bernier/Gwendoline/2019.

David Robbe
Team leader
INMED – Marseille
https://www.inmed.fr/

Invited by Giovanni Marsicano (Magendie)

Title

Disentangling the too many functions of the dorsal striatum in rats: from motor skill to sensitivity to motor cost

Abstract

A prominent theory in system neuroscience is that different forms of memories are stored in different brain regions/networks. Inside this framework, the dorsal striatum is believed to play a critical role in the storage and recall of motor skills and, more specifically, the goal-direct vs habitual selection of actions. In my talk, I will try demonstrate the conceptual weakness of these views by highlighting that tasks typically used to study motor skill do not separate high-level mnemonic/action selection functions from motivational constraints. I will present recent and ongoing work of our team (and others) that provide evidence that the dorsal striatum contribution to motor skill might be derived from a more fundamental contribution of this brain region to the sensitivity to movement costs, with potential implication to understand several brain disorders at the interface between movement and motivations.

Selected publications

Lost in time: Relocating the perception of duration outside the brain.

Robbe D. Neurosci Biobehav Rev. 2023 Oct;153:105312. doi: 10.1016/j.neubiorev.2023.105312. Epub 2023 Jul 17.PMID: 37467906 Review

The Dorsal Striatum Energizes Motor Routines.

Jurado-Parras MT, Safaie M, Sarno S, Louis J, Karoutchi C, Berret B, Robbe D. Curr Biol. 2020 Nov 16;30(22):4362-4372.e6. doi: 10.1016/j.cub.2020.08.049. Epub 2020 Sep 17. PMID: 32946750 Free article.

Turning the body into a clock: Accurate timing is facilitated by simple stereotyped interactions with the environment.

Safaie M, Jurado-Parras MT, Sarno S, Louis J, Karoutchi C, Petit LF, Pasquet MO, Eloy C, Robbe D. Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):13084-13093. doi: 10.1073/pnas.1921226117. Epub 2020 May 20. PMID: 32434909 Free PMC article.

Response outcomes gate the impact of expectations on perceptual decisions.

Hermoso-Mendizabal A, Hyafil A, Rueda-Orozco PE, Jaramillo S, Robbe D, de la Rocha J. Nat Commun. 2020 Feb 26;11(1):1057. doi: 10.1038/s41467-020-14824-w. PMID: 32103009

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Détails

Date :
mercredi 15 mai
Heure :
11:00
Catégories d’Évènement:
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