October 18 – 11:00am
Dmitri Rusakov (University College London, UK)
Monitoring variable efficacy of individual synapses with multiplexed imaging
October 20 – 9:00am
Christophe Leterrier (Aix-Marseille University, France)
The axonal cytoskeleton at the nanoscale
October 20 – 11:00am
Olga Garaschuk (University of Tübingen, Germany)
Deciphering the functional properties of mouse and human microglia
October 21 – 9:00am
Kirill Volynski (University College London, UK)
iGluSnFR imaging reveals the differential regulation of synchronous and asynchronous vesicular release at small central synapses
October 21 – 11:00am
Daniel Choquet (Bordeaux Neurocampus, France)
Nanoscale organization and function of excitatory synapses
October 25 – 9:00am
Timothy Ryan (Cornell University, USA)
Support your local synapse: vulnerabilities and control points in synapse function
October 25 – 11:00am
Dragomir Milovanovic (Charité University Clinic, Germany)
Phase separation at the synaptic boutons
October 28 – 9:00am
Tatiana Korotkova (University of Cologne, Germany)
Simple pleasures: neuronal regulation of feeding and social interactions
October 28 – 11:00am
Laurent Groc (Bordeaux Neurocampus, France)
Imaging membrane receptor dynamics: basics and role in neuropsychiatric disorders
October 29 – 9:00am
Andrea Volterra (University of Lausanne, Switzerland)
Use of 1D-to-3D two-photon Ca2+ imaging to decode the language of astrocyte communication
October 29 – 11:00am
Christian Henneberger (University of Bonn, Germany)
Visualizing the extracellular signalling of glutamate receptor ligands
November 2 – 9:00am
Anna Beyeler (Bordeaux Neurocampus, France)
Circuits dissection in emotional valence and anxiety: case studies on the amygdala and insular cortex
November 2 – 11:00am
Valentin Nagerl (Bordeaux Neurocampus, France)
Super-resolution microscopy for neuroscience: from basic principles to recent applications
November 3 – 9:00am
Michael Häusser (University College London)
TBA
November 3 – 11:00am
Gregory Giannone (Bordeaux Neurocampus, France)
TBA
November 3 – 5:30pm
Thomas Blanpied (University of Maryland, USA)
Dynamic control of synapse nanoarchitecture
About the course
In partnership with the Bordeaux Imaging Center
Venue: Bordeaux School of Neuroscience
Rapid advances in live imaging of targeted cellular morphologies and functions underpin the emerging revolution in our understanding of synapses, circuits, and behaviour. This Cajal course will assemble, as international faculty, leading experts in developing and exploiting cutting-edge imaging techniques that have been propelling such advances. How to combine genetically encoded fluorescence labelling with behavioural designs, micro-circuit monitoring, or single-molecule tracking, how to avoid pitfalls of having false-positive observations and inherent noise, how to best analyse your multi-dimensional data will be, among others, the recurrent subjects of the course. An intense programme of lectures and seminars will be combined with supervised, hands-on practical training modules and group assignments using experimental setups and tools provided by the world-leading research environment of the Bordeaux School of Neuroscience.
Course directors:
• Director: Dmitri Rusakov (UCL Queen Square Institute of Neurology, UK)
• Co-director: Tatiana Korotkova (Neuronal circuits and behaviour, MPI for Metabolism Research, Germany)
• Local director: Grégory Giannone (CNRS, IINS – UMR 5297, University of Bordeaux, France)