Lieu : Centre Broca Nouvelle-Aquitaine
Symposium organisé par Eric Boué-Grabot et Jérôme Baufreton
This symposium will gather recognized french and brazilian experts, who will present advances made in understanding the role of neuronal and glial purinergic receptors (P2X, P2Y and Adenosine receptors) in synaptic maturation or plasticity, neurodegenerative diseases and neuro-inflammatory disorders from single molecule and new opto-gated tools, to functional and behavioral neuroscience.
Programme
– 14:15 : introduction
– 14:20 : « Purinergic signaling in neurogenesis and neurodegeneration » par Hennig Ulrich, University of Sao Paolo, Brazil
– 14:45 : « P2X7 expressed by macrophages controls T-cell mediated autoimmune response » par Cécile Delarasse, Institut de la vision, Paris
– 15:10 : « Adenosine A2A receptor drives neuro-microglial dysfunction in Alzheimer’s Disease » par David Blum, Inserm Lille Neuroscience & Cognition, Lille
– 15:35 : « Unraveling the participation of the P2Y1 receptor in dopaminergic neuron death » par Roberta Andrejew, University of Sao Paolo, Brazil
– 16:00 : pause
– 16:30 : « How the use chemical photoswitches provides new insights into trimeric ion channel function » par Thomas Grutter, CNRS CBST, Strasbourg
– 16:55 : « Interaction between adenosine and NMDAR in the aged glutamatergic synapses » par Paula Poushina, IPMC, Valbonne
– 17:20 : « The paradoxical effect of the A2A receptor in the stabilization and elimination of synapses during development » par Sabine Lévi, ESPCI, PSL, Paris
– 17:45 : conclusion