Purinergic mediated neuroinflammation and brain disorders

Selected publications

• Increased surface P2X4 receptors by mutant SOD1 proteins contribute to ALS pathogenesis in SOD1-G93A mice
  Eléonore Bertin, Audrey Martinez, Anne Fayoux, Kevin Carvalho, Sara Carracedo, Pierre-Olivier Fernagut, Friedrich Koch-Nolte, David Blum, Sandrine S. Bertrand, Eric Boué-Grabot.
  Cell. Mol. Life Sci.. 2022-07-19. 79 (8)
  DOI: 10.1007/s00018-022-04461-5
• Pain hypersensitivity in a pharmacological mouse model of attention-deficit/hyperactivity disorder.
  Otmane Bouchatta, Franck Aby, Wahiba Sifeddine, Rabia Bouali-Benazzouz, Louison Brochoire, Houria Manouze, Pascal Fossat, Saadia Ba M’Hamed, Mohamed Bennis, Marc Landry.
  Proc. Natl. Acad. Sci. U.S.A.. 2022-07-19. 119 (30)
  DOI: 10.1073/pnas.2114094119
• Implication of Neuronal Versus Microglial P2X4 Receptors in Central Nervous System Disorders
  Alexia Duveau, Eléonore Bertin, Eric Boué-Grabot.
  Neurosci. Bull.. 2020-09-05.
  DOI: 10.1007/s12264-020-00570-y
• Implication of Neuronal Versus Microglial P2X4 Receptors in Central Nervous System Disorders
  Alexia Duveau, Eléonore Bertin, Eric Boué-Grabot.
  Neurosci. Bull.. 2020-09-05.
  DOI: 10.1007/s12264-020-00570-y
• Spinal Inhibition of GABAB Receptors by the Extracellular Matrix Protein Fibulin-2 in Neuropathic Rats
  Marie-Amélie Papon, Yves Le Feuvre, Gabriel Barreda-Gómez, Alexandre Favereaux, Fanny Farrugia, Rabia Bouali-Benazzouz, Frédéric Nagy, Rafael Rodríguez-Puertas, Marc Landry.
  Front. Cell. Neurosci.. 2020-07-15. 14
  DOI: 10.3389/fncel.2020.00214
• Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice
  Eléonore Bertin, Thomas Deluc, Kjara S. Pilch, Audrey Martinez, Johan-Till Pougnet, Evelyne Doudnikoff, Anne-Emilie Allain, Philine Bergmann, Marion Russeau, Estelle Toulmé, Erwan Bezard, Friedrich Koch-Nolte, Philippe Séguéla, Sabine Lévi, Bruno Bontempi, François Georges, Sandrine S. Bertrand, Olivier Nicole, Eric Boué-Grabot.
  Mol Psychiatry. 2020-01-08.
  DOI: 10.1038/s41380-019-0641-8
• Comparative Embryonic Spatio-Temporal Expression Profile Map of the Xenopus P2X Receptor Family
  Camille Blanchard, Eric Boué-Grabot, Karine Massé.
  Front. Cell. Neurosci.. 2019-07-26. 13
  DOI: 10.3389/fncel.2019.00340
• Acquisition of analgesic properties by the cholecystokinin (CCK)/CCK2 receptor system within the amygdala in a persistent inflammatory pain condition.
  Olivier Roca-Lapirot, Pascal Fossat, Sherie Ma, Karine Egron, Gabriella Trigilio, María-José López-González, João Covita, Rabia Bouali-Benazzouz, Alexandre Favereaux, Andrew L. Gundlach, Marc Landry.
  PAIN. 2019-02-01. 160 (2) : 345-357.
  DOI: 10.1097/j.pain.0000000000001408
• Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport
  Maria M Magiera, Satish Bodakuntla, Jakub Žiak, Sabrina Lacomme, Patricia Marques Sousa, Sophie Leboucher, Torben J Hausrat, Christophe Bosc, Annie Andrieux, Matthias Kneussel, Marc Landry, André Calas, Martin Balastik, Carsten Janke.
  EMBO J. 2018-11-12. 37 (23)
  DOI: 10.15252/embj.2018100440
• Neonatal 6-OHDA lesion model in mouse induces Attention-Deficit/ Hyperactivity Disorder (ADHD)-like behaviour
  Otmane Bouchatta, Houria Manouze, Rabia Bouali-benazzouz, Nóra Kerekes, Saadia Ba-M’hamed, Pascal Fossat, Marc Landry, Mohamed Bennis.
  Sci Rep. 2018-10-18. 8 (1)
  DOI: 10.1038/s41598-018-33778-0
• APE1/Ref-1 redox function contributes to inflammatory pain sensitization.
  Amira Zaky, Rabia Bouali-Benazzouz, Alexandre Favereaux, Gianluca Tell, Marc Landry.
  Experimental Neurology. 2018-09-01. 307 : 1-11.
  DOI: 10.1016/j.expneurol.2018.05.014
• MicroRNA and chronic pain: From mechanisms to therapeutic potential.
  María José López-González, Marc Landry, Alexandre Favereaux.
  Pharmacology & Therapeutics. 2017-12-01. 180 : 1-15.
  DOI: 10.1016/j.pharmthera.2017.06.001
• Modulation of Central Synapses by Astrocyte-Released ATP and Postsynaptic P2X Receptors
  Eric Boué-Grabot, Yuriy Pankratov.
  Neural Plasticity. 2017-01-01. 2017 : 1-11.
  DOI: 10.1155/2017/9454275
• Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation.
  W. Danquah, C. Meyer-Schwesinger, B. Rissiek, C. Pinto, A. Serracant-Prat, M. Amadi, D. Iacenda, J.-H. Knop, A. Hammel, P. Bergmann, N. Schwarz, J. Assuncao, W. Rotthier, F. Haag, E. Tolosa, P. Bannas, E. Boue-Grabot, T. Magnus, T. Laeremans, C. Stortelers, F. Koch-Nolte.
  Science Translational Medicine. 2016-11-23. 8 (366) : 366ra162-366ra162.
  DOI: 10.1126/scitranslmed.aaf8463
• P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons
  Johan-Till Pougnet, Benjamin Compans, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabot.
  Sci Rep. 2016-09-01. 6 (1)
  DOI: 10.1038/srep31836
• Cav1.2 and Cav1.3 L-type calcium channels independently control short- and long-term sensitization to pain.
  Houda Radwani, Maria José Lopez-Gonzalez, Daniel Cattaert, Olivier Roca-Lapirot, Eric Dobremez, Rabia Bouali-Benazzouz, Emelía Eiríksdóttir, Ülo Langel, Alexandre Favereaux, Mohammed Errami, Marc Landry, Pascal Fossat.
  J Physiol. 2016-07-03. 594 (22) : 6607-6626.
  DOI: 10.1113/jp272725
• Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.
  Michel Engeln, Matthieu F. Bastide, Estelle Toulmé, Benjamin Dehay, Mathieu Bourdenx, Evelyne Doudnikoff, Qin Li, Christian E. Gross, Eric Boué-Grabot, Antonio Pisani, Erwan Bezard, Pierre-Olivier Fernagut.
  Biological Psychiatry. 2016-03-01. 79 (5) : 354-361.
  DOI: 10.1016/j.biopsych.2014.07.007
• A New Mechanism of Receptor Targeting by Interaction between Two Classes of Ligand-Gated Ion Channels
  Michel Boris Emerit, Camille Baranowski, Jorge Diaz, Audrey Martinez, Julie Areias, Jeanine Alterio, Justine Masson, Eric Boué-Grabot, Michèle Darmon.
  J. Neurosci.. 2016-02-03. 36 (5) : 1456-1470.
  DOI: 10.1523/JNEUROSCI.2390-15.2016
• A secretagogin locus of the mammalian hypothalamus controls stress hormone release
  Roman A Romanov, Alán Alpár, Ming‐Dong Zhang, Amit Zeisel, André Calas, Marc Landry, Matthew Fuszard, Sally L Shirran, Robert Schnell, Árpád Dobolyi, Márk Oláh, Lauren Spence, Jan Mulder, Henrik Martens, Miklós Palkovits, Mathias Uhlen, Harald H Sitte, Catherine H Botting, Ludwig Wagner, Sten Linnarsson, Tomas Hökfelt, Tibor Harkany.
  EMBO J. 2014-11-27. 34 (1) : 36-54.
  DOI: 10.15252/embj.201488977
• ATP P2X receptors downregulate AMPA receptor trafficking and postsynaptic efficacy in hippocampal neurons.
  Johan-Till Pougnet, Estelle Toulme, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabot.
  Neuron. 2014-07-01. 83 (2) : 417-430.
  DOI: 10.1016/j.neuron.2014.06.005