TRAIN: Translational Research in Assistive and Interventional Neurotechnologies
Our team develops and investigates neurotechnologies through a translational approach spanning preclinical models and proof-of-concept clinical studies. We aim to understand the mechanisms underlying neuromodulation strategies for motor and cognitive disorders and to evaluate their feasibility and efficacy as both assistive and interventional neurotechnologies. Assistive neurotechnologies seek to improve motor or cognitive function while they are being applied, whereas interventional neurotechnologies seek to promote longer-lasting functional improvements by engaging neuroplasticity through repeated stimulation.
Mots clés
Apprentissage, Cognition, Démences, Interfaces humain-machine et Santé connectée, Motricité, Mémoire, Neurophysiologie, Plasticité des réseaux, brain stimulation, brain-machine interfaces, neuroengineering, neuromodulation, neuroprostheticsSelected publications
-
High-accuracy electrode implantation in deep brain structures using multi-camera neuronavigation in non-human primates
Ankur Gupta, Adrien Boissenin, Nikolaos Vardalakis, Mathieu Taillade, Hugues Orignac, Nathalie Biendon, Sandra Dovero, Tho-Hai Nguyen, Amirouche Sadoun, Fabien B Wagner.
J. Neural Eng.. 2025-10-14.
DOI: 10.1088/1741-2552/ae135b -
In vivo submillimeter diffusion MRI dataset of 9 macaque brains curated for tractography
Alex Valcourt Caron, Nadège Corbin, Adrien Boissenin, Ankur Gupta, Tho-Hai Nguyen, Serge Anandra, Sylvain Miraux, Maxime Descoteaux, Laurent Petit, Fabien B. Wagner.
Sci Data. 2025-07-11. 12 (1)
DOI: 10.1038/s41597-025-05350-9 -
A dynamical computational model of theta generation in hippocampal circuits to study theta-gamma oscillations during neurostimulation
Nikolaos Vardalakis, Amélie Aussel, Nicolas P. Rougier, Fabien B. Wagner.
eLife. 2023-02-14.
DOI: 10.7554/eLife.87356.3 -
Neuroprosthetics: from sensorimotor to cognitive disorders
Ankur Gupta, Nikolaos Vardalakis, Fabien B. Wagner.
Comm Biol. 2023-01-06.
DOI: 10.1038/s42003-022-04390-w
Team member(s)
Chercheurs, Praticiens hospitaliers...
Ingénieur(e)s, technicien(ne)s
Post-doctorant(s)
Doctorant(s)
Neuropsychologist(s) and speech therapist(s)
Ingénieur(s) hospitalier(s) et ARC