Susanna Pietropaolo

Scientific articles

• The role of gene-environment interactions in social dysfunction: focus on preclinical evidence from mouse studies
  Giulia Castellano, Johana Bonnet Da Silva, Susanna Pietropaolo.
  Neuropharmacology. 2024-10-01. : 110179.
  10.1016/j.neuropharm.2024.110179
• Autistic‐relevant behavioral phenotypes of a mouse model of cyclin‐dependent kinase‐like 5 deficiency disorder
  Nicola Mottolese, Oceane Coiffard, Celeste Ferraguto, Athanasios Manolis, Elisabetta Ciani, Susanna Pietropaolo.
  Autism Research. 2024-09-05.
  10.1002/aur.3226
• Therapeutic efficacy of the BKCa channel opener chlorzoxazone in a mouse model of Fragile X syndrome
  Celeste Ferraguto, Marion Piquemal-Lagoueillat, Valerie Lemaire, Maïté M. Moreau, Stefania Trazzi, Beatrice Uguagliati, Elisabetta Ciani, Sandrine S. Bertrand, Eric Louette, Bruno Bontempi, Susanna Pietropaolo.
  Neuropsychopharmacol.. 2024-09-02.
  10.1038/s41386-024-01956-6
• Early Administration of the Phytocannabinoid Cannabidivarin Prevents the Neurobehavioral Abnormalities Associated with the Fmr1-KO Mouse Model of Fragile X Syndrome
  Marika Premoli, William Fyke, Luigi Bellocchio, Valerie Lemaire, Marie Wolley-Roberts, Bruno Bontempi, Susanna Pietropaolo.
  Cells. 2023-07-25. 12(15) : 1927.
  10.3390/cells12151927
• Hyperacusis in the Adult Fmr1-KO Mouse Model of Fragile X Syndrome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels
  Celeste Ferraguto, Yohan Bouleau, Thibault Peineau, Didier Dulon, Susanna Pietropaolo.
  IJMS. 2023-07-24. 24(14) : 11863.
  10.3390/ijms241411863
• The Impact of Mild Chronic Stress and Maternal Experience in the Fmr1 Mouse Model of Fragile X Syndrome
  Enejda Subashi, Valerie Lemaire, Valeria Petroni, Susanna Pietropaolo.
  IJMS. 2023-07-13. 24(14) : 11398.
  10.3390/ijms241411398
• The Impact of Mild Chronic Stress and Maternal Experience in the Fmr1 Mouse Model of Fragile X Syndrome
  Enejda Subashi, Valerie Lemaire, Valeria Petroni, Susanna Pietropaolo.
  IJMS. 2023-07-13. 24(14) : 11398.
  10.3390/ijms241411398
• Mouse and rat ultrasonic vocalizations in neuroscience and neuropharmacology: State of the art and future applications
  Marika Premoli, Susanna Pietropaolo, Markus Wöhr, Nicola Simola, Sara Anna Bonini.
  Eur J of Neuroscience. 2023-03-26.
  10.1111/ejn.15957
• Early Neurobehavioral Characterization of the CD Mouse Model of Williams–Beuren Syndrome
  Silvia Giannoccaro, Celeste Ferraguto, Valeria Petroni, Coline Marcelly, Xavier Nogues, Victoria Campuzano, Susanna Pietropaolo.
  Cells. 2023-01-21. 12(3) : 391.
  10.3390/cells12030391
• Long-term behavioral effects of prenatal stress in the Fmr1-knock-out mouse model for fragile X syndrome
  Valeria Petroni, Enejda Subashi, Marika Premoli, Maurizio Memo, Valerie Lemaire, Susanna Pietropaolo.
  Front. Cell. Neurosci.. 2022-10-27. 16
  10.3389/fncel.2022.917183
• Editorial: Acoustic communication analysis for understanding animal behavior
  Sara Anna Bonini, Susanna Pietropaolo.
  Front. Behav. Neurosci.. 2022-08-03. 16
  10.3389/fnbeh.2022.991573
• Ultrasonic Vocalizations in Adult C57BL/6J Mice: The Role of Sex Differences and Repeated Testing
  Marika Premoli, Valeria Petroni, Ronald Bulthuis, Sara Anna Bonini, Susanna Pietropaolo.
  Front. Behav. Neurosci.. 2022-07-14. 16
  10.3389/fnbeh.2022.883353
• Editorial: Targeting Excitation-Inhibition Imbalance in Neurodevelopmental and Autism Spectrum Disorders
  Susanna Pietropaolo, Giovanni Provenzano.
  Front. Neurosci.. 2022-07-08. 16
  10.3389/fnins.2022.968115
• Scribble Controls Social Motivation Behavior through the Regulation of the ERK/Mnk1 Pathway
  Maïté M. Moreau, Susanna Pietropaolo, Jérôme Ezan, Benjamin J. A. Robert, Sylvain Miraux, Marlène Maître, Yoon Cho, Wim E. Crusio, Mireille Montcouquiol, Nathalie Sans.
  Cells. 2022-05-10. 11(10) : 1601.
  10.3390/cells11101601
• Autistic-like behavioral effects of prenatal stress in juvenile Fmr1 mice: the relevance of sex differences and gene-environment interactions.
  Valeria Petroni, Enejda Subashi, Marika Premoli, Markus Wöhr, Wim E. Crusio, Valerie Lemaire, Susanna Pietropaolo.
  Sci Rep. 2022-05-04. 12(1)
  10.1038/s41598-022-11083-1
• The role of the endocannabinoid system as a therapeutic target for autism spectrum disorder: Lessons from behavioral studies on mouse models
  Susanna Pietropaolo, Giovanni Marsicano.
  Neuroscience & Biobehavioral Reviews. 2022-01-01. 132 : 664-678.
  10.1016/j.neubiorev.2021.11.031
• Biotechnologies and Animals: The Impact of Genetic Engineering on Human-Animal Relationships
  Susanna Pietropaolo.
  The Palgrave Macmillan Animal Ethics Series. 2022-01-01. : 241-271.
  10.1007/978-3-030-85277-1_12
• Communication and social interaction in the cannabinoid‐type 1 receptor null mouse: Implications for autism spectrum disorder
  William Fyke, Marika Premoli, Victor Echeverry Alzate, José A. López‐Moreno, Valerie Lemaire‐Mayo, Wim E. Crusio, Giovanni Marsicano, Markus Wöhr, Susanna Pietropaolo.
  Autism Research. 2021-06-26. 14(9) : 1854-1872.
  10.1002/aur.2562
• The role of the endocannabinoid system in autism spectrum disorders: Evidence from mouse studies.
  Susanna Pietropaolo, Luigi Bellocchio, Inés Bouzón-Arnáiz, Benjamin K. Yee.
  Progress in Molecular Biology and Translational Science. 2020-01-01. : 183-208.
  10.1016/bs.pmbts.2020.04.016
• Potential Involvement of Impaired BKCa Channel Function in Sensory Defensiveness and Some Behavioral Disturbances Induced by Unfamiliar Environment in a Mouse Model of Fragile X Syndrome.
  Maria Isabel Carreno-Munoz, Fabienne Martins, Maria Carmen Medrano, Elisabetta Aloisi, Susanna Pietropaolo, Corentin Dechaud, Enejda Subashi, Guillaume Bony, Melanie Ginger, Abdelmalik Moujahid, Andreas Frick, Xavier Leinekugel.
  Neuropsychopharmacology. 2017-07-19. 43(3) : 492-502.
  10.1038/npp.2017.149
• Behavioral abnormalities in the Fmr1-KO2 mouse model of fragile X syndrome: The relevance of early life phases
  Julie Gaudissard, Melanie Ginger, Marika Premoli, Maurizio Memo, Andreas Frick, Susanna Pietropaolo.
  Autism Research. 2017-06-07. 10(10) : 1584-1596.
  10.1002/aur.1814
• Behavioral effects of chronic stress in the Fmr1 mouse model for fragile X syndrome.
  Valerie Lemaire-Mayo, Enejda Subashi, Nadia Henkous, Daniel Beracochea, Susanna Pietropaolo.
  Behavioural Brain Research. 2017-03-01. 320 : 128-135.
  10.1016/j.bbr.2016.11.051
• Omics analysis of mouse brain models of human diseases.
  Véronique Paban, Béatrice Loriod, Claude Villard, Luc Buee, David Blum, Susanna Pietropaolo, Yoon H. Cho, Sylvie Gory-Faure, Elodie Mansour, Ali Gharbi, Béatrice Alescio-Lautier.
  Gene. 2017-02-01. 600 : 90-100.
  10.1016/j.gene.2016.11.022
• Gene-Environment Interactions in Neurodevelopmental Disorders
  Susanna Pietropaolo, Wim E. Crusio, Joram Feldon.
  Neural Plasticity. 2017-01-01. 2017 : 1-2.
  10.1155/2017/9272804
• Genetic deletion of the Histone Deacetylase 6 exacerbates selected behavioral deficits in the R6/1 mouse model for Huntington’s disease.
  Alienor Ragot, Susanna Pietropaolo, Jean Vincent, Pauline Delage, Hongyu Zhang, Bernadette Allinquant, Xavier Leinekugel, André Fischer, Yoon H. Cho.
  Brain Behav. 2015-06-24. 5(9) : n/a-n/a.
  10.1002/brb3.361
• Sleep Physiology Alterations Precede Plethoric Phenotypic Changes in R6/1 Huntington’s Disease Mice.
  Fanny Lebreton, Sebastien Cayzac, Susanna Pietropaolo, Yannick Jeantet, Yoon H. Cho.
  PLoS ONE. 2015-05-12. 10(5) : e0126972.
  10.1371/journal.pone.0126972
• Chronic cannabinoid receptor stimulation selectively prevents motor impairments in a mouse model of Huntington’s disease.
  Susanna Pietropaolo, Luigi Bellocchio, Andrea Ruiz-Calvo, Magali Cabanas, Zhuowei Du, Manuel Guzmán, Maurice Garret, Yoon H. Cho.
  Neuropharmacology. 2015-02-01. 89 : 368-374.
  10.1016/j.neuropharm.2014.07.021
• Treatment Approaches in Rodent Models for Autism Spectrum Disorder.
  Susanna Pietropaolo, Wim E. Crusio, Francesca R. D’amato.
  Social Behavior from Rodents to Humans. 2015-01-01. : 325-340.
  10.1007/7854_2015_433
• Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice.
  Yu Zhang, Audrey Bonnan, Guillaume Bony, Isabelle Ferezou, Susanna Pietropaolo, Melanie Ginger, Nathalie Sans, Jean Rossier, Ben Oostra, Gwen LeMasson, Andreas Frick.
  Nat Neurosci. 2014-11-10. 17(12) : 1701-1709.
  10.1038/nn.3864
• Dietary supplementation of omega-3 fatty acids rescues fragile X phenotypes in Fmr1-Ko mice
  Susanna Pietropaolo, Mena Goubran, Corinne Joffre, Agnes Aubert, Valerie Lemaire-Mayo, Wim E. Crusio, Sophie Layé.
  Psychoneuroendocrinology. 2014-11-01. 49 : 119-129.
  10.1016/j.psyneuen.2014.07.002
• Early Social Enrichment Rescues Adult Behavioral and Brain Abnormalities in a Mouse Model of Fragile X Syndrome
  Diego Oddi, Enejda Subashi, Silvia Middei, Luigi Bellocchio, Valerie Lemaire-Mayo, Manuel Guzmán, Wim E Crusio, Francesca R D'Amato, Susanna Pietropaolo.
  Neuropsychopharmacol. 2014-10-28. 40(5) : 1113-1122.
  10.1038/npp.2014.291
• Rescue of fragile X syndrome phenotypes in Fmr1KO mice by a BKCa channel opener molecule
  Betty Hébert, Susanna Pietropaolo, Sandra Même, Béatrice Laudier, Anthony Laugeray, Nicolas Doisne, Angélique Quartier, Sandrine Lefeuvre, Laurence Got, Dominique Cahard, Frédéric Laumonnier, Wim E Crusio, Jacques Pichon, Arnaud Menuet, Olivier Perche, Sylvain Briault.
  Orphanet J Rare Dis. 2014-08-01. 9(1)
  10.1186/S13023-014-0124-6
• Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule
  Betty Hébert, Susanna Pietropaolo, Sandra Même, Béatrice Laudier, Anthony Laugeray, Nicolas Doisne, Angélique Quartier, Sandrine Lefeuvre, Laurence Got, Dominique Cahard, Frédéric Laumonnier, Wim E Crusio, Jacques Pichon, Arnaud Menuet, Olivier Perche, Sylvain Briault.
  Orphanet J Rare Dis. 2014-08-01. 9(1)
  10.1186/s13023-014-0124-6
• Environmental enrichment eliminates the anxiety phenotypes in a triple transgenic mouse model of Alzheimer’s disease.
  Susanna Pietropaolo, Joram Feldon, Benjamin K. Yee.
  Cogn Affect Behav Neurosci. 2014-02-04. 14(3) : 996-1008.
  10.3758/s13415-014-0253-3
• Monogenic mouse models of social dysfunction: Implications for autism
  D. Oddi, W.E. Crusio, F.R. D’Amato, S. Pietropaolo.
  Behavioural Brain Research. 2013-08-01. 251 : 75-84.
  10.1016/j.bbr.2013.01.002
• Early development of social deficits in APP and APP-PS1 mice
  Susanna Pietropaolo, Pauline Delage, Fanny Lebreton, Wim E. Crusio, Yoon H. Cho.
  Neurobiology of Aging. 2012-05-01. 33(5) : 1002.e17-1002.e27.
  10.1016/j.neurobiolaging.2011.09.012
• Sex-dependent changes in social behaviors in motor pre-symptomatic R6/1 mice
  Susanna Pietropaolo, Pauline Delage, Sebastien Cayzac, Wim E. Crusio, Yoon H. Cho.
  PLoS ONE. 2011-05-16. 6(5) : e19965.
  10.1371/journal.pone.0019965
• Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice
  Susanna Pietropaolo, Aurélie Guilleminot, Benoît Martin, Francesca R. D'Amato, Wim E. Crusio.
  PLoS ONE. 2011-02-22. 6(2) : e17073.
  10.1371/journal.pone.0017073
• Strain-dependent changes in acoustic startle response and its plasticity across adolescence in Mice
  Susanna Pietropaolo, Wim E. Crusio.
  Behav Genet. 2009-07-30. 39(6) : 623-631.
  10.1007/s10519-009-9291-y
• Age-related accumulation of Reelin in amyloid-like deposits
  Irene Knuesel, Myriel Nyffeler, Cecile Mormède, Mary Muhia, Urs Meyer, Susanna Pietropaolo, Benjamin K. Yee, Christopher R. Pryce, Frank M. LaFerla, Aline Marighetto, Joram Feldon.
  Neurobiology of Aging. 2009-05-01. 30(5) : 697-716.
  10.1016/j.neurobiolaging.2007.08.011
• Limited impact of social isolation on Alzheimer-like symptoms in a triple transgenic mouse model.
  Susanna Pietropaolo, Yan Sun, Ruixi Li, Corinne Brana, Joram Feldon, Benjamin K. Yee.
  Behavioral Neuroscience. 2009-01-01. 123(1) : 181-195.
  10.1037/a0013607
• The impact of voluntary exercise on mental health in rodents: a neuroplasticity perspective.
  Susanna Pietropaolo, Yan Sun, Ruixi Li, Corinne Brana, Joram Feldon, Benjamin K. Yee.
  Behavioural Brain Research. 2008-09-01. 192(1) : 42-60.
  10.1016/j.bbr.2008.03.014
• The postweaning social isolation in C57BL/6 mice: preferential vulnerability in the male sex.
  Susanna Pietropaolo, Philipp Singer, Joram Feldon, Benjamin K. Yee.
  Psychopharmacology. 2008-03-04. 197(4) : 613-628.
  10.1007/s00213-008-1081-3
• Age-dependent phenotypic characteristics of a triple transgenic mouse model of Alzheimer disease.
  Susanna Pietropaolo, Joram Feldon, Benjamin K. Yee.
  Behavioral Neuroscience. 2008-01-01. 122(4) : 733-747.
  10.1037/a0012520
• Nonphysical contact between cagemates alleviates the social isolation syndrome in C57BL/6 male mice.
  Susanna Pietropaolo, Joram Feldon, Benjamin K. Yee.
  Behavioral Neuroscience. 2008-01-01. 122(3) : 505-515.
  10.1037/0735-7044.122.3.505
• Bidirectional changes in water-maze learning following recombinant adenovirus-associated viral vector (rAAV)-mediated brain-derived neurotrophic factor expression in the rat hippocampus.
  Susanna Pietropaolo, Jean-Charles Paterna, Hansruedi Büeler, Joram Feldon, Benjamin K. Yee.
  Behavioural Pharmacology. 2007-09-01. 18(5-6) : 533-547.
  10.1097/fbp.0b013e3282da0bf6
• The behavioral sequela following the prevention of home-cage grid-climbing activity in C57BL/6 mice.
  Susanna Pietropaolo, Matti Mintz, Joram Feldon, Benjamin K. Yee.
  Behavioral Neuroscience. 2007-01-01. 121(2) : 345-355.
  10.1037/0735-7044.121.2.345
• The expression of prepulse inhibition of the acoustic startle reflex as a function of three pulse stimulus intensities, three prepulse stimulus intensities, and three levels of startle responsiveness in C57BL6/J mice.
  Benjamin K. Yee, Tilly Chang, Susanna Pietropaolo, Joram Feldon.
  Behavioural Brain Research. 2005-09-01. 163(2) : 265-276.
  10.1016/j.bbr.2005.05.013
• Long-term effects of the periadolescent environment on exploratory activity and aggressive behaviour in mice: social versus physical enrichment.
  S PIETROPAOLO, I BRANCHI, F CIRULLI, F CHIAROTTI, L ALOE, E ALLEVA.
  Physiology & Behavior. 2004-05-01. 81(3) : 443-453.
  10.1016/j.physbeh.2004.02.022