Marie-Laure Arotcarena

Scientific articles

• Nigral ATP13A2 depletion induces Parkinson’s disease-related neurodegeneration in a pilot study in non-human primates
  Joanna Sikora, Sandra Dovero, Rémi Kinet, Marie-Laure Arotcarena, Sylvain Bohic, Erwan Bezard, Pierre-Olivier Fernagut, Benjamin Dehay.
  npj Parkinsons Dis.. 2024-08-01. 10(1)
  10.1038/s41531-024-00757-4
• Modeling Parkinson’s Disease in Primates
  Erwan Bezard, Margaux Teil, Marie-Laure Arotcarena, Gregory Porras, Qin Li, Benjamin Dehay.
  Cold Spring Harb Perspect Med. 2024-06-10. : a041612.
  10.1101/cshperspect.a041612
• Reconsidering α-Synuclein inclusion pathology in neurons, mice, and humans with an antibody sensing NAC engagement during α-Synuclein amyloid conversion
  Francesca De Giorgi, Ænora Letourneur, Marianna Kashyrina, Federica Zinghirino, Sandra Dovero, Nathalie Dutheil, Leslie-Ann Largitte, Marie-Laure Arotçarena, Erwan Bezard, Marie-Hélène Canron, Wassilios Meissner, Francesco De Nuccio, Dario Domenico Lofrumento, Florent Laferrière, François Ichas.
  Preprint - Research Square. 2024-02-07.
  10.21203/rs.3.rs-3921168/v1
• Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain
  Margaux Teil, Sandra Dovero, Mathieu Bourdenx, Marie-Laure Arotcarena, Morgane Darricau, Gregory Porras, Marie-Laure Thiolat, Inés Trigo-Damas, Celine Perier, Cristina Estrada, Nuria Garcia-Carrillo, María Trinidad Herrero, Miquel Vila, José A. Obeso, Erwan Bezard, Benjamin Dehay.
  npj Parkinsons Dis.. 2023-09-19. 9(1)
  10.1038/s41531-023-00579-w
• Monitoring α-synuclein aggregation.
  Juan Estaun-Panzano, Marie-Laure Arotcarena, Erwan Bezard.
  Neurobiology of Disease. 2023-01-01. 176 : 105966.
  10.1016/j.nbd.2022.105966
• Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology
  Margaux Teil, Sandra Dovero, Mathieu Bourdenx, Marie-Laure Arotcarena, Sandrine Camus, Gregory Porras, Marie-Laure Thiolat, Ines Trigo-Damas, Celine Perier, Cristina Estrada, Nuria Garcia-Carrillo, Michele Morari, Wassilios G Meissner, María Trinidad Herrero, Miquel Vila, Jose A Obeso, Erwan Bezard, Benjamin Dehay.
  Brain. 2022-03-14. 145(3) : 1001-1017.
  10.1093/brain/awab374
• Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques
  Marie-Laure Arotcarena, Sandra Dovero, Nathalie Biendon, Nathalie Dutheil, Vincent Planche, Erwan Bezard, Benjamin Dehay.
  Front. Bioeng. Biotechnol.. 2021-11-15. 9
  10.3389/fbioe.2021.762209
• Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment
  Morgane Darricau, Marie-Hélène Canron, Marion Bosc, Marie-Laure Arotçarena, Mégane Le Quang, Benjamin Dehay, Erwan Bezard, Vincent Planche.
  Neurobiology of Aging. 2021-11-01. 107 : 53-56.
  10.1016/j.neurobiolaging.2021.07.009
• A New Rise of Non-Human Primate Models of Synucleinopathies
  Margaux Teil, Marie-Laure Arotcarena, Benjamin Dehay.
  Biomedicines. 2021-03-09. 9(3) : 272.
  10.3390/biomedicines9030272
• Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
  Federico N. Soria, Chiara Paviolo, Evelyne Doudnikoff, Marie-Laure Arotcarena, Antony Lee, Noémie Danné, Amit Kumar Mandal, Philippe Gosset, Benjamin Dehay, Laurent Groc, Laurent Cognet, Erwan Bezard.
  Nat Commun. 2020-07-10. 11(1)
  10.1038/s41467-020-17328-9
• Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
  M. Bourdenx, A. Nioche, S. Dovero, M.-L. Arotcarena, S. Camus, G. Porras, M.-L. Thiolat, N. P. Rougier, A. Prigent, P. Aubert, S. Bohic, C. Sandt, F. Laferrière, E. Doudnikoff, N. Kruse, B. Mollenhauer, S. Novello, M. Morari, T. Leste-Lasserre, I. Trigo Damas, M. Goillandeau, C. Perier, C. Estrada, N. Garcia-Carrillo, A. Recasens, N. N. Vaikath, O. M. A. El-Agnaf, M. T. Herrero, P. Derkinderen, M. Vila, J. A. Obeso, B. Dehay, E. Bezard.
  Sci. Adv.. 2020-05-01. 6(20) : eaaz9165.
  10.1126/sciadv.aaz9165
• Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates
  Marie-Laure Arotcarena, Sandra Dovero, Alice Prigent, Mathieu Bourdenx, Sandrine Camus, Gregory Porras, Marie-Laure Thiolat, Maddalena Tasselli, Philippe Aubert, Niels Kruse, Brit Mollenhauer, Ines Trigo Damas, Cristina Estrada, Nuria Garcia-Carrillo, Nishant N Vaikath, Omar M A El-Agnaf, Maria Trinidad Herrero, Miquel Vila, Jose A Obeso, Pascal Derkinderen, Benjamin Dehay, Erwan Bezard.
  Brain. 2020-05-01. 143(5) : 1462-1475.
  10.1093/brain/awaa096
• Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in non-human primates
  M. Bourdenx, A. Nioche, S. Dovero, M.-L. Arotcarena, S. Camus, G. Porras, M.-L. Thiolat, N. P. Rougier, A. Prigent, P. Aubert, S. Bohic, C. Sandt, F. Laferrière, E. Doudnikoff, N. Kruse, B. Mollenhauer, S. Novello, M. Morari, T. Leste-Lasserre, I. Trigo Damas, M. Goillandeau, C. Perier, C. Estrada, N. Garcia-Carrillo, A. Recasens, N. N. Vaikath, O. M. A. El-Agnaf, M. Trinidad Herrero, P. Derkinderen, M. Vila, J. A. Obeso, B. Dehay, E. Bezard.
  . 2019-10-31.
  10.1101/825216
• Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies
  Marie-Laure Arotcarena, Mathieu Bourdenx, Nathalie Dutheil, Marie-Laure Thiolat, Evelyne Doudnikoff, Sandra Dovero, Andrea Ballabio, Pierre-Olivier Fernagut, Wassilios G. Meissner, Erwan Bezard, Benjamin Dehay.
  JCI Insight. 2019-08-22. 4(16)
  10.1172/jci.insight.129719
• Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery
  Marie-Laure Arotcarena, Margaux Teil, Benjamin Dehay.
  Cells. 2019-06-09. 8(6) : 565.
  10.3390/cells8060565
• Are synucleinopathies prion-like disorders?,Les synucléinopathies sont-elles des maladies à prions ?
  M.-L. Arotçarena, B. Dehay.
  Pratique Neurologique - FMC. 2018-04-01. 9(2) : 145-151.
  10.1016/j.praneu.2018.02.006