Jean-Luc Morel

Scientific articles

• Physical exercise restores adult neurogenesis deficits induced by simulated microgravity
  Alexandra Gros, Fandilla Marie Furlan, Vanessa Rouglan, Alexandre Favereaux, Bruno Bontempi, Jean-Luc Morel.
  npj Microgravity volume. 2024-06-21. 10(69)
  10.1038/s41526-024-00411-6
• Hypergravity Increases Blood–Brain Barrier Permeability to Fluorescent Dextran and Antisense Oligonucleotide in Mice
  David Dubayle, Arnaud Vanden-Bossche, Tom Peixoto, Jean-Luc Morel.
  Cells. 2023-02-24. 12(5) : 734.
  10.3390/cells12050734
• Characterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl− Current in Vascular Myocytes
  Jean-Luc Morel, Nathalie Mokrzycki, Guy Lippens, Hervé Drobecq, Pierre Sautière, Michel Hugues.
  Toxins. 2022-11-10. 14(11) : 780.
  10.3390/toxins14110780
• Simulated Microgravity Subtlety Changes Monoamine Function across the Rat Brain
  Alexandra Gros, Léandre Lavenu, Jean-Luc Morel, Philippe De Deurwaerdère.
  IJMS. 2021-10-29. 22(21) : 11759.
  10.3390/ijms222111759
• Targeting Pdzrn3 maintains adult blood-brain barrier and central nervous system homeostasis
  Florian Gueniot, Sebastien Rubin, Pauline Bougaran, Alice Abelanet, Jean Luc Morel, Bruno Bontempi, Carole Proust, Pascale Dufourcq, Thierry Couffinhal, Cecile Duplàa.
  J Cereb Blood Flow Metab. 2021-10-13. : 0271678X2110489.
  10.1177/0271678X211048981
• Effects of centrifugation and whole-body vibrations on blood–brain barrier permeability in mice
  David Dubayle, Arnaud Vanden-Bossche, Mathieu Beraneck, Laurence Vico, Jean-Luc Morel.
  npj Microgravity. 2020-01-07. 6(1)
  10.1038/s41526-019-0094-z
• Cytolethal distending toxin induces the formation of transient messenger-rich ribonucleoprotein nuclear invaginations in surviving cells
  Lamia Azzi-Martin, Wencan He, Christelle Péré-Védrenne, Victoria Korolik, Chloé Alix, Martina Prochazkova-Carlotti, Jean-Luc Morel, Emilie Le Roux-Goglin, Philippe Lehours, Mojgan Djavaheri-Mergny, Christophe F. Grosset, Christine Varon, Pierre Dubus, Armelle Ménard.
  PLoS Pathog. 2019-09-30. 15(9) : e1007921.
  10.1371/journal.ppat.1007921
• Presenilin 1 mutation decreases both calcium and contractile responses in cerebral arteries
  Xavier Toussay, Jean-Luc Morel, Nathalie Biendon, Lolita Rotureau, François-Pierre Legeron, Marie-Charlotte Boutonnet, Yoon H. Cho, Nathalie Macrez.
  Neurobiology of Aging. 2017-10-01. 58 : 201-212.
  10.1016/j.neurobiolaging.2017.06.015
• Changes in C57BL6 mouse hippocampal transcriptome induced by hypergravity mimic acute corticosterone-induced stress
  Alice Pulga, Yves Porte, Jean-Luc Morel.
  Front. Mol. Neurosci.. 2016-12-26. 9
  10.3389/fnmol.2016.00153
• TRPP2 modulates ryanodine- and inositol-1,4,5-trisphosphate receptors-dependent Ca2+ signals in opposite ways in cerebral arteries
  Azzedine Abdi, Claire Mazzocco, François-Pierre Légeron, Blaise Yvert, Nathalie Macrez, Jean-Luc Morel.
  Cell Calcium. 2015-11-01. 58(5) : 467-475.
  10.1016/j.ceca.2015.07.003
• Blood brain barrier precludes the cerebral arteries to intravenously-injected antisense oligonucleotide.
  Raphael Boursereau, Arnaud Donadieu, Fabrice Dabertrand, David Dubayle, Jean-Luc Morel.
  European Journal of Pharmacology. 2015-01-01. 747 : 141-149.
  10.1016/j.ejphar.2014.11.027
• Up-regulation of ryanodine receptor expression increases the calcium-induced calcium release and spontaneous calcium signals in cerebral arteries from hindlimb unloaded rats
  Jean-Luc Morel, Fabrice Dabertrand, Yves Porte, Anne Prevot, Nathalie Macrez.
  Pflugers Arch - Eur J Physiol. 2013-11-15. 466(8) : 1517-1528.
  10.1007/s00424-013-1387-9
• Effect of aging on calcium signaling in C57Bl6J mouse cerebral arteries
  Carole Georgeon-Chartier, Céline Menguy, Anne Prévot, Jean-Luc Morel.
  Pflugers Arch - Eur J Physiol. 2012-12-14. 465(6) : 829-838.
  10.1007/s00424-012-1195-7
• The 22nd Ion Channel Meeting, September 2011, France
  Jean-Marc Goaillard, Laurent Groc, Sabine Lévi, Massimo Mantegazza, Fabrice Matifat, Jean-Luc Morel, Anne Baron-Forster.
  Channels. 2012-05-01. 6(3) : 149-153.
  10.4161/chan.20795
• Spaceflight regulates ryanodine receptor subtype 1 in portal vein myocytes in the opposite way of hypertension
  Fabrice Dabertrand, Yves Porte, Nathalie Macrez, Jean-Luc Morel.
  Journal of Applied Physiology. 2012-02-01. 112(3) : 471-480.
  10.1152/japplphysiol.00733.2011
• Learning on Jupiter, learning on the Moon: The dark side of the G-force. Effects of gravity changes on neurovascular unit and modulation of learning and memory
  Yves Porte, Jean-Luc Morel.
  Front. Behav. Neurosci.. 2012-01-01. 6
  10.3389/fnbeh.2012.00064
• Comparison between gentamycin and exon skipping treatments to restore ryanodine receptor subtype 2 functions in mdx mouse duodenum myocytes
  Fabrice Dabertrand, Jean Mironneau, Morgana Henaff, Nathalie Macrez, Jean-Luc Morel.
  European Journal of Pharmacology. 2010-02-01. 628(1-3) : 36-41.
  10.1016/j.ejphar.2009.11.034
• The decrease of expression of ryanodine receptor sub-type 2 is reversed by gentamycin sulphate in vascular myocytes from mdx mice
  Jean-Luc Morel, Fabrice Dabertrand, Nicolas Fritz, Morgana Henaff, Jean Mironneau, Nathalie Macrez.
  Journal of Cellular and Molecular Medicine. 2009-02-27. 13(9b) : 3122-3130.
  10.1111/j.1582-4934.2009.00718.x
• Acetylcholine evokes an InsP3R1-dependent transient Ca 2+ signal in rat duodenum myocytes
  Nicolas Fritz, Fabrice Dabertrand, Jean Mironneau, Nathalie Macrez, Jean-Luc Morel.
  Can. J. Physiol. Pharmacol.. 2008-09-01. 86(9) : 626-632.
  10.1139/Y08-067
• Full length ryanodine receptor subtype 3 encodes spontaneous calcium oscillations in native duodenal smooth muscle cells
  Fabrice Dabertrand, Jean Mironneau, Nathalie Macrez, Jean-Luc Morel.
  Cell Calcium. 2008-08-01. 44(2) : 180-189.
  10.1016/j.ceca.2007.11.009
• Acetylcholine-induced Ca2+ oscillations are modulated by a Ca2+ regulation of InsP3R2 in rat portal vein myocytes
  Nicolas Fritz, Jean Mironneau, Nathalie Macrez, Jean-Luc Morel.
  Pflugers Arch - Eur J Physiol. 2007-11-20. 456(2) : 277-283.
  10.1007/s00424-007-0379-z
• RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle
  N. Fritz, J.-L. Morel, L. H. Jeyakumar, S. Fleischer, P. D. Allen, J. Mironneau, N. Macrez.
  Journal of Cell Science. 2007-10-09. 120(21) : 3784-3791.
  10.1242/jcs.009415
• Role of RYR3 splice variants in calcium signaling in mouse nonpregnant and pregnant myometrium
  Fabrice Dabertrand, Nicolas Fritz, Jean Mironneau, Nathalie Macrez, Jean-Luc Morel.
  American Journal of Physiology-Cell Physiology. 2007-09-01. 293(3) : C848-C854.
  10.1152/ajpcell.00069.2007
• Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells
  Fabrice Dabertrand, Jean-Luc Morel, Vincenzo Sorrentino, Jean Mironneau, Chantal Mironneau, Nathalie Macrez.
  Cell Calcium. 2006-07-01. 40(1) : 11-21.
  10.1016/j.ceca.2006.03.008
• Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells
  Fabrice Dabertrand, Jean-Luc Morel, Vincenzo Sorrentino, Jean Mironneau, Chantal Mironneau, Nathalie Macrez.
  Cell Calcium. 2006-07-01. 40(1) : 11-21.
  10.1016/j.ceca.2006.03.008
• Ryanodine receptor subtype 2 encodes Ca2+ oscillations activated by acetylcholine via the M2 muscarinic receptor/cADP-ribose signalling pathway in duodenum myocytes
  N. Fritz.
  Journal of Cell Science. 2005-05-15. 118(10) : 2261-2270.
  10.1242/jcs.02344
• Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes
  Jean-Luc Morel, Lala Rakotoarisoa, Loice H. Jeyakumar, Sidney Fleischer, Chantal Mironneau, Jean Mironneau.
  J. Biol. Chem.. 2004-02-25. 279(20) : 21287-21293.
  10.1074/jbc.M311124200
• Crucial role of type 2 inositol 1,4,5-trisphosphate receptors for acetylcholine-induced Ca2+ oscillations in vascular myocytes
  J.-L. Morel.
  Arteriosclerosis, Thrombosis, and Vascular Biology. 2003-09-01. 23(9) : 1567-1575.
  10.1161/01.ATV.0000089013.82552.5D
• Identification and function of ryanodine receptor subtype 3 in non-pregnant mouse myometrial cells
  J. Mironneau, N. Macrez, J.L. Morel, V. Sorrentino, C. Mironneau.
  The Journal of Physiology. 2002-02-01. 538(3) : 707-716.
  10.1113/jphysiol.2001.013046
• Calcium signalling through nucleotide receptor P2X1 in rat portal vein myocytes
  J. Mironneau, F. Coussin, J. L. Morel, C. Barbot, L. H. Jeyakumar, S. Fleischer, C. Mironneau.
  The Journal of Physiology. 2001-10-01. 536(2) : 339-350.
  10.1111/j.1469-7793.2001.0339c.xd
• Ca2+ signals mediated by Ins(1,4,5)P3-gated channels in rat ureteric myocytes
  François-Xavier BOITTIN, Frédéric COUSSIN, Jean-Luc MOREL, Guillaume HALET, Nathalie MACREZ, Jean MIRONNEAU.
  Biochem. J.. 2000-07-01. 349(1) : 323.
  10.1042/0264-6021:3490323
• Requirement of ryanodine receptor subtypes 1 and 2 for Ca2+-induced Ca2+ release in vascular myocytes
  Frédéric Coussin, Nathalie Macrez, Jean-Luc Morel, Jean Mironneau.
  J. Biol. Chem.. 2000-03-24. 275(13) : 9596-9603.
  10.1074/jbc.275.13.9596
• A βγ dimer derived from G13 transduces the angiotensin AT1 receptor signal to stimulation of Ca2+ channels in rat portal vein myocytes
  Nathalie Macrez, Jean-Luc Morel, Frank Kalkbrenner, Patricia Viard, Günter Schultz, Jean Mironneau.
  J. Biol. Chem.. 1997-09-12. 272(37) : 23180-23185.
  10.1074/jbc.272.37.23180
• Specific G(q) protein involvement in muscarinic M3 receptor-induced phosphatidylinositol hydrolysis and Ca2+ release in mouse duodenal myocytes
  J. L. Morel, N. Macrez, J. Mironneau.
  British Journal of Pharmacology. 1997-05-01. 121(3) : 451-458.
  10.1038/sj.bjp.0701157
• G protein heterotrimer Gα13β1γ3 couples the angiotensin AT(1A) receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytes
  Nathalie Macrez-Leprêtre, Frank Kalkbrenner, Jean-Luc Morel, Günter Schultz, Jean Mironneau.
  J. Biol. Chem.. 1997-04-11. 272(15) : 10095-10102.
  10.1074/jbc.272.15.10095
• Effects of phospholipase C inhibitors on Ca2+ channel stimulation and Ca2+ release from intracellular stores evoked by α1A- and α2A-adrenoceptors in rat portal vein myocytes
  Nathalie Macrez-Leprêtre, Jean-Luc Morel, Jean Mironneau.
  Biochemical and Biophysical Research Communications. 1996-01-01. 218(1) : 30-34.
  10.1006/bbrc.1996.0006
• A Gi1-2-protein is required for α2A-adrenoceptor-induced stimulation of voltage-dependent Ca2+ channels in rat portal vein myocytes
  Nathalie Macrez-Lepretre, Javier Ibarrondo, Serge Arnaudeau, Jean -Luc Morel, Gilles Guillon, Jean Mironneau.
  Pflugers Arch.. 1995-08-01. 430(4) : 590-592.
  10.1007/BF00373897