Jean-Christophe Helbling
Engineer/Technician
Ingénieur d'étude (IE) / INRAe/ Team
Nutrition and Neuropsychiatric Symptom Dimensions (NutriPsy)
Nutrineuro
Mechanisms of neural circuit sensitivity to altered nutritional status (FoodCircus)
Nutrineuro
/ Contact
+33 5 57 57 60 18
www.orcid.org/0000-0001-7407-0114
Scientific articles
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Time-restricted feeding prevents memory impairments induced by obesogenic diet consumption, via hippocampal thyroid hormone signaling
Molecular Metabolism. 2024-12-01. 90 : 102061.
10.1016/j.molmet.2024.102061 -
Impact of dietary vitamin A on striatal function in adult rats.
The FASEB Journal. 2023-07-01. 37(8)
10.1096/fj.202300133r -
Memory deficits in a juvenile rat model of type 1 diabetes are due to excess 11β-HSD1 activity, which is upregulated by high glucose concentrations rather than insulin deficiency
Diabetologia. 2023-06-10.
10.1007/s00125-023-05942-3 -
Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer’s disease: Evidence from clinicopathological and preclinical studies
Neurobiology of Disease. 2021-12-01. 161 : 105542.
10.1016/j.nbd.2021.105542 -
Retinoic acid increases glucocorticoid receptor phosphorylation via cyclin-dependent kinase
Molecular and Cellular Neuroscience. . 82 : 96-104.
https://doi.org/10.1016/j.mcn.2017.05.001 -
Combined Gene Expression and Chromatin Immunoprecipitation From a Single Mouse Hippocampus.
Curr Protoc. 2021-02. 1(2) : e33.
10.1002/cpz1.33 -
Spontaneous intake of essential oils after a negative postnatal experience has long-term effects on blood transcriptome in chickens.
Sci Rep. 2020-11-26. 10(1)
10.1038/s41598-020-77732-5 -
Dietary vitamin A supplementation prevents early obesogenic diet-induced microbiota, neuronal and cognitive alterations
Int J Obes. 2020-11-22.
10.1038/s41366-020-00723-z -
Reshaping circadian metabolism in the suprachiasmatic nucleus and prefrontal cortex by nutritional challenge
Proc Natl Acad Sci USA. 2020-11-10. : 202016589.
10.1073/pnas.2016589117 -
Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits.
Cell Metabolism. 2020-04-01. 31(4) : 755-772.e7.
10.1016/j.cmet.2020.02.012 -
Unraveling the effects of the gut microbiota composition and function on horse endurance physiology.
Sci Rep. 2019-07-03. 9(1)
10.1038/s41598-019-46118-7 -
Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner
Brain Behav Immun.. 2019-03-11.
10.1016/j.bbi.2019.03.006 -
Pharmacological restoration of gut barrier function in stressed neonates partially reverses long-term alterations associated with maternal separation
Psychopharmacology. 2019-05-01. 236(5) : 1583-1596.
10.1007/s00213-019-05252-w -
Corticosteroid-Binding Globulin deficiency specifically impairs contextual and recognition memory consolidation in male mice
Neuroendocrinology. 2019-03-25.
10.1159/000499827 -
Insulin treatment partially prevents cognitive and hippocampal alterations as well as glucocorticoid dysregulation in early-onset insulin-deficient diabetic rats.
Psychoneuroendocrinology. 2018-07-01. 93 : 72-81.
10.1016/j.psyneuen.2018.04.016 -
Retinoic acid increases glucocorticoid receptor phosphorylation via cyclin-dependent kinase 5.
Molecular and Cellular Neuroscience. 2017-07-01. 82 : 96-104.
10.1016/j.mcn.2017.05.001 -
Nasal airway epithelial cell IL-6 and FKBP51 gene expression and steroid sensitivity in asthmatic children.
PLoS ONE. 2017-05-11. 12(5) : e0177051.
10.1371/journal.pone.0177051 -
Diabetes and Insulin Injection Modalities: Effects on Hepatic and Hippocampal Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Juvenile Diabetic Male Rats.
Front. Endocrinol.. 2017-04-18. 8
10.3389/fendo.2017.00081 -
Chronic stress does not further exacerbate the abnormal psychoneuroendocrine phenotype of Cbg-deficient male mice.
Psychoneuroendocrinology. 2016-08-01. 70 : 33-37.
10.1016/j.psyneuen.2016.04.014 -
Role of corticosteroid binding globulin in emotional reactivity sex differences in mice.
Psychoneuroendocrinology. 2014-12-01. 50 : 252-263.
10.1016/j.psyneuen.2014.07.029 -
Role of corticosteroid binding globulin in the fast actions of glucocorticoids on the brain.
Steroids. 2014-03-01. 81 : 109-115.
10.1016/j.steroids.2013.10.013 -
Stress and glucocorticoid regulation of NR4A genes in mice.
Journal of Neuroscience Research. 2014-02-19. 92(7) : 825-834.
10.1002/jnr.23366 -
Corticosteroid-binding globulin contributes to the neuroendocrine phenotype of mice selected for extremes in stress reactivity.
Journal of Endocrinology. 2013-09-17. 219(3) : 217-229.
10.1530/JOE-13-0255 -
Critical role of plasma corticosteroid-binding-globulin during stress to promote glucocorticoid delivery to the brain: impact on memory retrieval.
Endocrinology. 2012-10-01. 153(10) : 4766-4774.
10.1210/en.2012-1485 -
Intrinsic expression of transcortin in neural cells of the mouse brain: a histochemical and molecular study.
J Exp Biol. 2012-09-20. 216(2) : 245-252.
10.1242/jeb.076893 -
Maintaining RNA integrity in a homogeneous population of mammary epithelial cells isolated by Laser Capture Microdissection.
BMC Cell Biol. 2010-12-01. 11(1)
10.1186/1471-2121-11-95 -
Terminal differentiation of goat mammary tissue during pregnancy requires the expression of genes involved in immune functions.
Physiological Genomics. 2009-12-01. 40(1) : 61-82.
10.1152/physiolgenomics.00032.2009 -
Persistence of plant DNA sequences in the blood of dairy cows fed with genetically modified (Bt176) and conventional corn silage.
J. Agric. Food Chem.. 2009-01-05. 57(2) : 509-516.
10.1021/jf802262c -
The olig family: phylogenetic analysis and early gene expression in Xenopus tropicalis.
Dev Genes Evol. 2007-06-07. 217(7) : 485-497.
10.1007/s00427-007-0158-z -
Translational efficiency of casein transcripts in the mammary tissue of lactating ruminants.
Reprod. Nutr. Dev.. 2006-09-01. 46(5) : 567-578.
10.1051/rnd:2006028