Bruno Brochet

Scientific articles

• Vulnerability of Thalamic Nuclei at CSF Interface During the Entire Course of Multiple Sclerosis
  Ismail Koubiyr, Takayuki Yamamoto, Simon Blyau, Reda A. Kamroui, Boris Mansencal, Vincent Planche, Laurent Petit, Manojkumar Saranathan, Romain Casey, Aurélie Ruet, Bruno Brochet, José V. Manjón, Vincent Dousset, Pierrick Coupé, Thomas Tourdias,.
  Neurol Neuroimmunol Neuroinflamm. 2024-05-01. 11(3)
  10.1212/NXI.0000000000200222
• Improvements in quality of life over 2 years with cladribine tablets in people with relapsing multiple sclerosis: The CLARIFY-MS study
  Bruno Brochet, Alessandra Solari, Jeannette Lechner-Scott, Fredrik Piehl, Dawn Langdon, Raymond Hupperts, Krzysztof Selmaj, Francesco Patti, Luis Brieva, Eva Maria Maida, Nektaria Alexandri, Andrzej Smyk, Axel Nolting, Birgit Keller, Xavier Montalban, Eva Kubala Havrdova.
  Mult Scler. 2023-11-18.
  10.1177/13524585231205962
• Natalizumab Treatment Induces Proinflammatory CD4 T Cells Preferentially in the Integrin β7+ Compartment
  Mélanie Nguyen Ky, Adrien Duran, Iris Hasantari, Agnès Bru, Mathilde Deloire, Bruno Brochet, Aurélie Ruet, Nathalie Schmitt.
  Neurol Neuroimmunol Neuroinflamm. 2023-09-22. 10(6) : e200166.
  10.1212/NXI.0000000000200166
• Differential vulnerability of thalamic nuclei in multiple sclerosis.
  Simon Blyau, Ismail Koubiyr, Manojkumar Saranathan, Pierrick Coupé, Mathilde Deloire, Julie Charré-Morin, Aurore Saubusse, Bei Zhang, Brian Rutt, Vincent Dousset, Bruno Brochet, Aurélie Ruet, Thomas Tourdias.
  Mult Scler. 2022-08-12. 29(2) : 295-300.
  10.1177/13524585221114247
• Altered functional brain states predict cognitive decline 5 years after a clinically isolated syndrome
  Ismail Koubiyr, Tommy AA Broeders, Mathilde Deloire, Bruno Brochet, Thomas Tourdias, Jeroen JG Geurts, Menno Michiel Schoonheim, Aurélie Ruet.
  Mult Scler. 2022-06-23. : 135245852211014.
  10.1177/13524585221101470
• Cognitive Impairment in Secondary Progressive Multiple Sclerosis: Effect of Disease Duration, Age, and Progressive Phenotype
  Bruno Brochet, Pierre Clavelou, Gilles Defer, Jérôme De Seze, Céline Louapre, Eloi Magnin, Aurélie Ruet, Catherine Thomas-Anterion, Patrick Vermersch.
  Brain Sciences. 2022-01-29. 12(2) : 183.
  10.3390/brainsci12020183
• Cognitive Rehabilitation in Multiple Sclerosis in the Period from 2013 and 2021: A Narrative Review
  Bruno Brochet.
  Brain Sciences. 2021-12-30. 12(1) : 55.
  10.3390/brainsci12010055
• Validation of a Brief Computerized Cognitive Assessment in Multiple Sclerosis (BCCAMS) and comparison with reference batteries
  Nicolas Maubeuge, Mathilde SA Deloire, Bruno Brochet, Julie Charré-Morin, Aurore Saubusse, Aurélie Ruet.
  Mult Scler. 2021-11-12. : 135245852110540.
  10.1177/13524585211054006
• Prevalence, Severity, and Clinical Management of Brain Incidental Findings in Healthy Young Adults: MRi-Share Cross-Sectional Study
  Aïcha Soumaré, Naka Beguedou, Alexandre Laurent, Bruno Brochet, Constance Bordes, Sandy Mournet, Emmanuel Mellet, Edwige Pereira, Clothilde Pollet, Morgane Lachaize, Marie Mougin, Ami Tsuchida, Hugues Loiseau, Thomas Tourdias, Christophe Tzourio, Bernard Mazoyer, Stéphanie Debette.
  Front. Neurol.. 2021-05-20. 12
  10.3389/FNEUR.2021.675244
• Insights on the Relationship Between Hippocampal Connectivity and Memory Performances at the Early Stage of Multiple Sclerosis.
  Juliette Boscheron, Aurélie Ruet , Mathilde Deloire, Julie Charré-Morin, Aurore Saubusse, Bruno Brochet , Thomas Tourdias , Ismail Koubiyr .
  Front. Neurol.. 2021-05-19. 12
  10.3389/fneur.2021.667531
• Structural constraints of functional connectivity drive cognitive impairment in the early stages of multiple sclerosis
  Ismail Koubiyr, Mathilde Deloire, Bruno Brochet, Pierre Besson, Julie Charré-Morin, Aurore Saubusse, Thomas Tourdias, Aurélie Ruet.
  Mult Scler. 2020-12-07. : 135245852097180.
  10.1177/1352458520971807
• Validation of the French version of the Minimal Assessment of Cognitive Function in Multiple Sclerosis (MACFIMS)
  Nicolas Maubeuge, Mathilde S.A. Deloire, Bruno Brochet, Nathalie Ehrlé, Julie Charré-Morin, Aurore Saubusse, Aurélie Ruet.
  Multiple Sclerosis and Related Disorders. 2020-12-01. : 102692.
  10.1016/j.msard.2020.102692
• BEST-MS: A prospective head-to-head comparative study of natalizumab and fingolimod in active relapsing MS
  Mikael Cohen, Lydiane Mondot, Florence Bucciarelli, Béatrice Pignolet, David-Axel Laplaud, Sandrine Wiertlewski, Bruno Brochet, Aurélie Ruet, Gilles Defer, Nathalie Derache, Patrick Vermersch, Hélène Zephir, Marc Debouverie, Guillaume Mathey, Eric Berger, Chrystelle Cappé, Pierre Labauge, Clarisse Carra, Jérôme De Seze, Kevin Bigaut, David Brassat, Christine Lebrun-Frenay.
  Mult Scler. 2020-10-30. : 135245852096914.
  10.1177/1352458520969145
• Effect of cognitive rehabilitation on neuropsychological and semiecological testing and on daily cognitive functioning in multiple sclerosis: The REACTIV randomized controlled study.
  D. Lamargue, I. Koubiyr, M. Deloire, A. Saubusse, J. Charre-Morin, A. Moroso, P. Coupé, B. Brochet, A. Ruet.
  Journal of the Neurological Sciences. 2020-08-01. 415 : 116929.
  10.1016/j.jns.2020.116929
• Evaluation of emotional disorders before and during treatment with interferon beta in patients with multiple sclerosis
  Jean-Christophe Ouallet, Françoise Radat, Alain Creange, Mohamed Abdellaoui, Olivier Heinzlef, Claire Giannesini, Patrick Hautecoeur, Delphine Lamargue Hamel, Mathilde Deloire, Bruno Brochet, Anne-Sophie Jean Deleglise, Philippe Lehert.
  Journal of the Neurological Sciences. 2020-06-01. 413 : 116739.
  10.1016/j.jns.2020.116739
• Double‐blind , randomized controlled trial of therapeutic plasma exchanges vs sham exchanges in moderate‐to‐severe relapses of multiple sclerosis
  Bruno Brochet, Mathilde Deloire, Christine Germain, Jean‐Christophe Ouallet, Linda Wittkop, Cécile Dulau, Paul Perez, Florian Thevenot, Jérome De Sèze, Hélène Zéphir, Patrick Vermersch, Sophie Pittion, Marc Debouverie, David‐Axel Laplaud, Pierre Clavelou, Aurélie Ruet.
  J Clin Apher. 2020-05-05. 35(4) : 281-289.
  10.1002/jca.21788
• Dynamic modular-level alterations of structural-functional coupling in clinically isolated syndrome.
  Ismail Koubiyr, Pierre Besson, Mathilde Deloire, Julie Charre-Morin, Aurore Saubusse, Thomas Tourdias, Bruno Brochet, Aurélie Ruet.
  Brain. 2019-09-05. 142(11) : 3428-3439.
  10.1093/brain/awz270
• Longitudinal study of functional brain network reorganization in clinically isolated syndrome.
  Ismail Koubiyr, Mathilde Deloire, Pierre Besson, Pierrick Coupé, Cécile Dulau, Jean Pelletier, Thomas Tourdias, Bertrand Audoin, Bruno Brochet, Jean-Philippe Ranjeva, Aurélie Ruet.
  Mult Scler. 2018-11-27. 26(2) : 188-200.
  10.1177/1352458518813108
• Differential Gray Matter Vulnerability in the 1 Year Following a Clinically Isolated Syndrome
  Ismail Koubiyr, Mathilde Deloire, Pierrick Coupé, Cécile Dulau, Pierre Besson, Amandine Moroso, Vincent Planche, Thomas Tourdias, Bruno Brochet, Aurélie Ruet.
  Front. Neurol.. 2018-10-11. 9
  10.3389/fneur.2018.00824
• Preliminary evidence of the cerebellar role on cognitive performances in clinically isolated syndrome.
  Amandine Moroso, Aurélie Ruet, Delphine Lamargue-Hamel, Fanny Munsch, Mathilde Deloire, Jean-Christophe Ouallet, Stéphanie Cubizolle, Julie Charré-Morin, Aurore Saubusse, Thomas Tourdias, Vincent Dousset, Bruno Brochet.
  Journal of the Neurological Sciences. 2018-02-01. 385 : 1-6.
  10.1016/j.jns.2017.11.037
• Regional hippocampal vulnerability in early multiple sclerosis: Dynamic pathological spreading from dentate gyrus to CA 1
  Vincent Planche, Ismail Koubiyr, José E. Romero, José V. Manjon, Pierrick Coupé, Mathilde Deloire, Vincent Dousset, Bruno Brochet, Aurélie Ruet, Thomas Tourdias.
  Hum. Brain Mapp.. 2018-01-13. 39(4) : 1814-1824.
  10.1002/hbm.23970
• Cerebellar Assessment in Early Multiple Sclerosis.
  Amandine Moroso, Aurélie Ruet, Mathilde Deloire, Delphine Lamargue-Hamel, Stéphanie Cubizolle, Julie Charré-Morin, Aurore Saubusse, Bruno Brochet.
  Cerebellum. 2016-11-04. 16(2) : 607-611.
  10.1007/s12311-016-0831-8
• Deciphering Depressive Mood in Relapsing-Remitting and Progressive Multiple Sclerosis and Its Consequence on Quality of Life.
  Delphine Lamargue Hamel, Mathilde Deloire, Aurélie Ruet, Julie Charré-Morin, Aurore Saubusse, Jean-Christophe Ouallet, Bruno Brochet.
  PLoS ONE. 2015-11-10. 10(11) : e0142152.
  10.1371/journal.pone.0142152
• Information processing speed impairment and cerebellar dysfunction in relapsing-remitting multiple sclerosis.
  Aurélie Ruet, Delphine Hamel, Mathilde S.A. Deloire, Julie Charré-Morin, Aurore Saubusse, Bruno Brochet.
  Journal of the Neurological Sciences. 2014-12-01. 347(1-2) : 246-250.
  10.1016/j.jns.2014.10.008
• Cognitive impairment differs between primary progressive and relapsing-remitting MS.
  Aurélie Ruet, Mathilde Deloire, Julie Charré-Morin, Delphine Hamel, Bruno Brochet.
  Neurology. 2013-04-16. 80(16) : 1501-1508.
  10.1212/wnl.0b013e31828cf82f
• A new computerised cognitive test for the detection of information processing speed impairment in multiple sclerosis.
  Aurélie Ruet, Mathilde SA Deloire, Julie Charré-Morin, Delphine Hamel, Bruno Brochet.
  Mult Scler. 2013-03-04. 19(12) : 1665-1672.
  10.1177/1352458513480251
• Cognitive impairment, health-related quality of life and vocational status at early stages of multiple sclerosis: a 7-year longitudinal study.
  Aurélie Ruet, Mathilde Deloire, Delphine Hamel, Jean-Christophe Ouallet, Klaus Petry, Bruno Brochet.
  J Neurol. 2012-10-19. 260(3) : 776-784.
  10.1007/s00415-012-6705-1
• MRI predictors of cognitive outcome in early multiple sclerosis.
  M.S.A. Deloire, A. Ruet, D. Hamel, M. Bonnet, V. Dousset, B. Brochet.
  Neurology. 2011-03-29. 76(13) : 1161-1167.
  10.1212/wnl.0b013e318212a8be
• Early cognitive impairment in multiple sclerosis predicts disability outcome several years later.
  Mathilde Deloire, Aurélie Ruet, Delphine Hamel, Melissa Bonnet, Bruno Brochet.
  Mult Scler. 2010-03-01. 16(5) : 581-587.
  10.1177/1352458510362819