Monthly conference (PhD seminar) – Anna Mitchell

Anna S Mitchell
Associate Professor
Department of Experimental Psychology, Oxford University, United Kingdomhttps://www.psy.ox.ac.uk/people/anna-mitchell

On Zoom

https://u-bordeaux-fr.zoom.us/j/82168794846?pwd=ZzhpeVVGbkVRa3NZRC9aMmhacXdaUT09

ID de réunion : 821 6879 4846
Code secret : 33000

Title

Thalamocortical interactions involving the mediodorsal thalamus during learning and decision-making in mammals

Abstract

Anatomical evidence in mammals shows that the mediodorsal thalamus (MD) is a key component within wider frontal thalamocortical networks. Accordingly, damage to, or disruption of MD function impairs specific types of learning and decision-making in humans and animal models. Yet, the underlying mechanisms behind the influence of MD on the frontal cortex during these higher order cognitive processes remain unknown. In this talk, I will discuss behavioural and cognitive evidence from lesion work, neuroimaging, and neurophysiology experiments that helps to decipher the influence of the MD on higher cognitive processes governed by the frontal cortex.

Key publications

• Corticocortical and Thalamocortical Changes in Functional Connectivity and White Matter Structural Integrity after Reward-Guided Learning of Visuospatial Discriminations in Rhesus Monkeys. Journal article

  Pelekanos V. et al, (2020), J Neurosci, 40, 7887 – 7901

   

• Critical role for the mediodorsal thalamus in permitting rapid reward-guided updating in stochastic reward environments. Journal article

  Chakraborty S. et al, (2016), Elife, 5

   

• Evidence for Mediodorsal Thalamus and Prefrontal Cortex Interactions during Cognition in Macaques. Journal article

  Browning PGF. et al, (2015), Cereb Cortex, 25, 4519 – 4534

   

• The mediodorsal thalamus as a higher order thalamic relay nucleus important for learning and decision-making. Journal article

  Mitchell AS., (2015), Neurosci Biobehav Rev, 54, 76 – 88

   

• Retrosplenial Cortical Contributions to Anterograde and Retrograde Memory in the Monkey. Journal article

  Buckley MJ. and Mitchell AS., (2016), Cereb Cortex, 26, 2905 – 2918

Organized by Bordeaux Neurocampus, NBA and Bordeaux Neurocampus Graduate Program