Venue : Centre Broca Nouvelle-Aquitaine
Symposium organized by Eric Boué-Grabot and Jérôme Baufreton
This symposium will gather recognized french and brazilian experts, who will present advances made in understanding the role of neuronal and glial purinergic receptors (P2X, P2Y and Adenosine receptors) in synaptic maturation or plasticity, neurodegenerative diseases and neuro-inflammatory disorders from single molecule and new opto-gated tools, to functional and behavioral neuroscience.
Programm
– 14:15 : introduction
– 14:20 : “Purinergic signaling in neurogenesis and neurodegeneration” by Hennig Ulrich, University of Sao Paolo, Brazil
– 14:45 : “P2X7 expressed by macrophages controls T-cell mediated autoimmune response” by Cécile Delarasse, Institut de la vision, Paris
– 15:10 : “Adenosine A2A receptor drives neuro-microglial dysfunction in Alzheimer’s Disease” by David Blum, Inserm Lille Neuroscience & Cognition, Lille
– 15:35 : “Unraveling the participation of the P2Y1 receptor in dopaminergic neuron death” by Roberta Andrejew, University of Sao Paolo, Brazil
– 16:00 : coffee break
– 16:30 : “How the use chemical photoswitches provides new insights into trimeric ion channel function” by Thomas Grutter, CNRS CBST, Strasbourg
– 16:55 : “Interaction between adenosine and NMDAR in the aged glutamatergic synapses” by Paula Poushina, IPMC, Valbonne
– 17:20 : “The paradoxical effect of the A2A receptor in the stabilization and elimination of synapses during development” by Sabine Lévi, ESPCI, PSL, Paris
– 17:45 : conclusion