Yoon Cho, Aliénior Ragot in Brain Behavior
Epigenetics is not yet the solution for Huntington’s disease
Mise en ligne : 4 April 2018
Commented publications
Matthieu Bastide, Erwan Bézard et al. in Neurobiol Dis.
Involvement of transcriptional mechanisms in L-DOPA induced dyskinesia
Mise en ligne : 4 April 2018
Martine Cador, Muriel Darnaudery inNeuropsychopharmacology
Unlimited sucrose consumption during adolescence generates a depressive-like phenotype in adulthood
Mise en ligne : 3 April 2018
Clémentine Bosch-Bouju,Thomas Larrieu, Sophie Layé inCell Reports
Endocannabinoid-Mediated Plasticity in Nucleus Accumbens Controls Vulnerability to Anxiety after Social Defeat Stress. (Pdf file) Clementine Bosch-Bouju,Thomas Larrieu, Louisa Linders,Olivier J. Manzoni and Sophie Laye / Cell Reports 16, 1–6 August 2, 2016 Laboratoire NutriNeuro / Bordeaux Neurocampus La relation entre la consommation d’Oméga 3 et l’adaptation au stress ou à l’anxiété se précise. En 2011…
Mise en ligne : 22 March 2018
Benard G, Bezard E, Marsicano G, Pouvreau S. in Neurobiol Dis.
MitoBrain, Putting energy into the brain. Benard G, Bezard E, Marsicano G, Pouvreau S. Neurobiol Dis. 2016 Jun;90:1-2. doi: 10.1016/j.nbd.2016.03.021. The MitoBrain meeting, which was held in Bordeaux on October 1-3 2014, brought together worldwide experts on the different aspects of mitochondrial physiology and pathology in the brain. The special issue of Neurobiology of Disease covers…
Mise en ligne : 22 March 2018
P. de Deurwaerdère et G. Di Giovanni inProg Neurobiol
De Deurwaerdère P, Di Giovanni G. Serotonergic modulation of the activity of mesencephalic dopaminergic systems: Therapeutic implications. Review. Prog Neurobiol. 2016 Mar 22. pii: S0301-0082(15)30096-4. 2016 review. Philippe de Deurwaerdère : Professeur de Neurosciences et Neuropharmacologie / Team leader : Neurochemistry, deep brain stimulation and Parkinson’s disease / Université de Bordeaux / Institut des Maladies Neurodégénératives…
Mise en ligne : 22 March 2018
Thomas Tourdias et al. inStroke
Bigourdan A, Munsch F, Coupé P, Guttmann CR, Sagnier S, Renou P, Debruxelles S, Poli M, Dousset V, Sibon I, Tourdias T. Early Fiber Number Ratio Is a Surrogate of Corticospinal Tract Integrity and Predicts Motor Recovery After Stroke. Stroke. 2016 Apr;47(4):1053-9. 2016 Thomas Tourdias est membre du Team ‘Glia-neuron interactions’ Group leader: Stéphane Oliet, PhD…
Mise en ligne : 22 March 2018
How does fear freezes us?
Midbrain circuits for defensive behaviour. Tovote P, Esposito MS, Botta P, Chaudun F, Fadok JP, Markovic M, Wolff SB, Ramakrishnan C, Fenno L, Deisseroth K, Herry C, Arber S, Lüthi A, Friedrich Miescher Nature. 2016 Jun 1;534(7606):206-12. doi: 10.1038/nature17996. Biozentrum, Department of Cell Biology, University of Basel, 4056 Basel, Switzerland. INSERM, Neurocentre Magendie, U862, 146…
Mise en ligne : 22 March 2018
A.Contarino et N. Morisot inNeuropharmacology
The CRF1 and the CRF2 receptor mediate recognition memory deficits and vulnerability induced by opiate withdrawal. Morisot N, Contarino A. Neuropharmacology. 2016 Feb 18;105:500-507. doi: 10.1016/j.neuropharm.2016.02.021 Nadège Morisot est post-doc au Dorit Ron’s Lab, Department of Neurology, University of California San Francisco, California, 94158, United States. Angelo Contarino /Bordeaux University, PhD, Team leader: Stress Cognitive…
Mise en ligne : 22 March 2018
P.Branchereau, D.Cattaert et al. in Scientific Reports
Depolarizing GABA/glycine synaptic events switch from excitation to inhibition during frequency increases. Branchereau P, Cattaert D, Delpy A, Allain AE, Martin E, Meyrand P. Sci Rep. 2016 Feb 25;6:21753. doi: 10.1038/srep21753. By acting on their ionotropic chloride channel receptor, GABA and glycine represent the major inhibitory amino acid transmitters of the central nervous system. These…
Mise en ligne : 22 March 2018
Daniela Cota et al. in Diabetes
Inhibiting Microglia Expansion Prevents Diet-induced Hypothalamic and Peripheral Inflammation. André C, Guzman-Quevedo O, Rey C, Rémus-Borel J, Clark S, Castellanos-Jankiewicz A, Ladeveze E, Leste-Lasserre T, Nadjar A, Abrous DN, Laye S, Cota D. Diabetes. 2016 Nov 30. pii: db160586. [Epub ahead of print] PMID: 27903745 This work was carried out in collaboration with the laboratories of…
Mise en ligne : 21 March 2018
François Georges et al. inNature Communications
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis. Glangetas C, Massi L, Fois GR, Jalabert M, Girard D, Diana M, Yonehara K, Roska B, Xu C, Lüthi A, Caille S, Georges F. Nat Commun. 2017 Feb 20;8:14456. doi: 10.1038/ncomms14456. Une publication soutenu par le LabEx BRAIN Abstract NMDA-receptor-dependent plasticity in the…
Mise en ligne : 20 March 2018
P-V Piazza et al. inNeuron
March 23rd, 2017 The CB1 Receptor as the Cornerstone of Exostasis. Pier Vincenzo Piazza, Daniela Cota, and Giovanni Marsicano. Neuron (2017),Neuron 93, March 22, 2017 ª 2017 Elsevier Inc. 1/j.neuron.2017.02.002/ Volume 93, Issue 6, p1252–1274, 22 March 2017 Giovanni Marsicano DVM, PhD Group Leader Group “Endocannabinoids and Neuroadaptation », Daniela Cota, MD,Group Leader, Group “Energy Balance and…
Mise en ligne : 20 March 2018
K. Guillem & S. Ahmed in Cerebral Cortex
Preference for Cocaine is Represented in the Orbitofrontal Cortex by an Increased Proportion of Cocaine Use-Coding Neurons, Karine Guillem, Serge H. Ahmed. Cereb Cortex 1-14.DOI: https://doi.org/10.1093/cercor/bhw398a Serge Ahmed, team leader: Pathological decison-making in addiction / IMN https://doi.org/10.1093/cercor/bhw398a Information in french: La cocaïne est la deuxième drogue illicite la plus utilisée en Europe. Heureusement, tous les usagers de cocaïne…
Mise en ligne : 20 March 2018
Pierre Philip et al. in Scientific Reports
Le 3 avril 2017 Virtual human as a new diagnostic tool, a proof of concept study in the field of major depressive disorders. Pierre Philip, Jean-Arthur Micoulaud-Franchi, Patricia Sagaspe, Etienne De Sevin, Jérôme Olive, Stéphanie Bioulac & Alain Sauteraud Scientific Reports 7, Article number: 42656 (2017) doi:10.1038/srep4265 12 January 2017 Dans Sciences et Avenir…
Mise en ligne : 20 March 2018
Guillaume Lucas in Molecular Psychiatry
Inducing a long-term potentiation in the dentate gyrus is sufficient to produce rapid antidepressant-like effects. Kanzari A, Bourcier-Lucas C, Freyssin A, Abrous DN, Haddjeri N, Lucas G. Inducing a long-term potentiation in the dentate gyrus is sufficient to produce rapid antidepressant-like effects. Mol Psychiatry. 2017 May 9. Information in french: L’un des principaux défis de la…
Mise en ligne : 20 March 2018
Thomas Tourdias et al. inBrain
June 6th, 2017 Thalamic alterations remote to infarct appear as focal iron accumulation and impact clinical outcome. Kuchcinski G, Munsch F, Lopes R, Bigourdan A, Su J, Sagnier S, Renou P, Pruvo JP, Rutt BK, Dousset V, Sibon I, Tourdias T. Brain. 2017 May 25. doi: 10.1093/brain/awx114. [Epub ahead of print] Post-stroke outcome includes not only…
Mise en ligne : 20 March 2018
S.Parkes, E. Coutureau et al. inCerebral Cortex
June 29th, 2017 Insular and Ventrolateral Orbitofrontal Cortices Differentially Contribute to Goal-Directed Behavior in Rodents. Parkes SL, Ravassard PM, Cerpa JC, Wolff M, Ferreira G, Coutureau E. Cereb Cortex. 2017 May 25:1-13. doi: 10.1093/cercor/bhx132. [Epub ahead of print] PMID: 28541407 CNRS, Institut de Neurosciences Cognitives et Intégratives d’Aquitaine, UMR 5287, Université de Bordeaux. / INRA, Nutrition…
Mise en ligne : 20 March 2018
Daniel Choquet and Yann Humeau in Nature
Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors. Penn A.C., Zhang C.L., Georges F., Royer L., Breillat C., Hosy E., Petersen J.D., Humeau Y. and Choquet D. Nature, le 13 septembre 2017. DOI : 10.1038/nature23658 Institute for Interdisciplinary Neuroscience (IINS) / Bordeaux Neurocampus / Campus Carreire / Université de Bordeaux …
Mise en ligne : 20 March 2018
Laurent Groc et al. dans Nature communications
Laurent Groc et al. in Nature communications Single receptor imaging in the intact brain : finally there !! The March 17, 2016 Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices Juan A. Varela, Julien P. Dupuis, Laetitia Etchepare, Agnès Espana, Laurent Cognet & Laurent Groc. Nature Communications 7, Article number: 10947…
Mise en ligne : 20 March 2018
J-M Israel, S. Oliet et P. Ciofi inFront Neurosci.
The July 20, 2016 Israel JM, Oliet SH, Ciofi P. Electrophysiology of Hypothalamic Magnocellular Neurons In vitro: A Rhythmic Drive in Organotypic Cultures and Acute Slices. Front Neurosci. 2016 Mar 31;10:109. 2016 This is a follow-up paper of our recent study concerning the pulsatile activity of hypothalamic neuroendocrine oxytocin neurons (Israel et al., 2014; see previous presentationand movie). A…
Mise en ligne : 20 March 2018
Ronan Chereau, Valentin Nagerl et al. in PNAS
Janaury 23rd, 2017 STED imaging reveals activity-dependent plasticity of axon morphology linked to changes in action potential conduction velocity by Ronan Chereau, Ezequiel Saraceno, Julie Angibaud, Daniel Cattaert and U. Valentin Nägerl Publication date: January 23, 2017 in Proceedings of the National Academy of Sciences (PNAS) Valentin Nagerl : Group leader Synaptic Plasticity and Super-Resolution…
Mise en ligne : 20 March 2018
G. Ferreira, P. Trifilieff et al. in eNeuro
Impact of Early Consumption of High-Fat Diet on the Mesolimbic Dopaminergic System. Naneix F, Tantot F, Glangetas C, Kaufling J, Janthakhin Y, Boitard C, De Smedt-Peyrusse V, Pape JR, Vancassel S, Trifilieff P, Georges F, Coutureau E, Ferreira G. eNeuro. 2017 Jun 1;4(3). pii: ENEURO.0120-17.2017. doi: 10.1523/ENEURO.0120-17.2017. eCollection 2017 May Une Publication NutriNeuro (Guillaume Ferreira /…
Mise en ligne : 20 March 2018
Sophie Layé et al. inJNeurosci
Amplification of mGlu5-endocannabinoid signaling rescues behavioral and synaptic deficits in a mouse model of adolescent and adult dietary polyunsaturated fatty acids imbalance. Antonia Manduca, Anissa Bara, Thomas Larrieu, Olivier Lassalle, Corinne Joffre, Sophie Layé and Olivier J. Manzoni / Journal of Neuroscience 19 June 2017, 3516-16; DOI Poor Adolescent Diet May Influence Brain and Behavior…
Mise en ligne : 12 March 2018
Aude Retailleau et al. inCurrent Biology
Spatial Rule Learning and Corresponding CA1 Place Cell Reorientation Depend on Local Dopamine Release. Aude Retailleau and Genela Morris. Current Biology 28 , 1–11, March 19, 2018
Mise en ligne : 12 March 2018
Nora Abrous et al. inMolecular Psychiatry
Depleting adult dentate gyrus neurogenesis increases cocaine-seeking behavior.
Mise en ligne : 12 March 2018
Mathieu Wolff, Fabien Alcaraz et al. in eLife
Thalamocortical and corticothalamic pathways differentially contribute to goal-directed behaviors in the rat.
Mise en ligne : 7 March 2018
M.Bourdenx, B. Dehay et al. inScientific Reports
Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model. Mathieu Bourdenx, Sandra Dovero, Marie-Laure Thiolat, Erwan Bezard & Benjamin Dehay.
Mise en ligne : 5 March 2018
Xavier Leinekugel et al. in Neuropsychopharm.
Maria Isabel Carreno-Munoz, Fabienne Martins, Maria Carmen Medrano, Elisabetta Aloisi, Susanna Pietropaolo, Corentin Dechaud, Enejda Subashi, Guillaume Bony, Melanie Ginger, Abdelmalik Moujahid, Andreas Frick & Xavier Leinekugel (2017). Potential involvement of impaired BKCa channel function in sensory defensiveness and some behavioral disturbances induced by unfamiliar environment in a mouse model of FXS. Neuropsychopharmacology, Jul 19 (in…
Mise en ligne : 5 March 2018
Getting out of the Shadow: Extracellular Brain Spaces Unveiled
Super-resolution imaging of the extracellular space in living brain tissue. Tonnesen J, VVGK Inavalli and Nägerl UV. Cell. 2018 Feb 22;172(5):1108-1121.e15. doi: 10.1016/j.cell.2018.02.007. Prof. U. Valentin Nägerl, PhD Institut Interdisciplinaire de Neurosciences (IINS) CNRS UMR 5297 / Université de Bordeaux / Centre Broca Nouvelle-Aquitaine / Bordeaux Neurocampus / Email : The extracellular space (ECS) of the brain provides the physical…
Mise en ligne : 2 March 2018
J.B. Sibarita, A. Beghin et al. in Nature Methods
Localization-based super-resolution imaging meets high-content screening.
Mise en ligne : 9 January 2018
E. Aloisi, A. Frick et al. in Nature Communication
Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice. Aloisi E, Le Corf K, Dupuis J, Zhang P, Ginger M, Labrousse V, Spatuzza M, Georg Haberl M, Costa L, Shigemoto R, Tappe-Theodor A, Drago F, Vincenzo Piazza P, Mulle C, Groc L, Ciranna L, Catania MV, Frick A. Nat…
Mise en ligne : 9 January 2018
J.B. Sibarita, A. Beghin et al. in Nature Methods
Localization-based super-resolution imaging meets high-content screening. Beghin A, Kechkar A, Butler C, Levet F, Cabillic M, Rossier O, Giannone G, Galland R, Choquet D, Sibarita JB. Nat Methods. 2017 Oct 30. doi: 10.1038/nmeth.4486. [Epub ahead of print] Jean-Baptiste Sibarita team leader et Anne Beghin: Quantitative Imaging of the Cell Institut Interdisciplinaire de Neurosciences / Bordeaux Neurocampus…
Mise en ligne : 9 January 2018
E. Aloisi, A. Frick et al. in Nature Communication
Le 21 novembre 2017 Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice. Aloisi E, Le Corf K, Dupuis J, Zhang P, Ginger M, Labrousse V, Spatuzza M, Georg Haberl M, Costa L, Shigemoto R, Tappe-Theodor A, Drago F, Vincenzo Piazza P, Mulle C, Groc L, Ciranna L, Catania MV,…
Mise en ligne : 21 November 2017
IMN and GIN in Nature Communication
The challenge of mapping the human connectome based on diffusion tractography. Nature Communications, doi:10.1038/s41467-017-01285-x. Maier-Hein, K. H., Neher, P. F., Houde, J.-C., Côté, M.-A., Garyfallidis, E., Zhong, J., et al. (2017). The challenge of mapping the human connectome based on diffusion tractography. Nature Communications, 1–13. http://doi.org/10.1038/s41467-017-01285-x > Sorry, in french! Cartographier le « connectome » humain requiert d’identifier les…
Mise en ligne : 20 November 2017
Joana Ferreira and Thomas Papouin ineLife
Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses. Ferreira JS, Papouin T, Ladépêche L, Yao A, Langlais VC, Bouchet D, Dulong J, Mothet JP, Sacchi S, Pollegioni L, Paoletti P, Oliet SHR, Groc L. Elife. 2017 Jun 9;6. pii: e25492. doi: 10.7554/eLife.25492. Laurent Groc: Interdisciplinary Institute for NeuroSciences, CNRS , Bordeaux, France Stéphane Oliet: Neurocentre Magendie, Inserm,…
Mise en ligne : 9 June 2017
Christophe Mulle et al. in Nat Rev Neurosci.
Operation and plasticity of hippocampal CA3 circuits: implications for memory encoding/ Rebola N, Carta M, Mulle C. Nat Rev Neurosci. 2017 Apr;18(4):208-220. Review. The CA3 region of the hippocampus is important for rapid encoding of memory. Computational theories have proposed specific roles in hippocampal function and memory for the sparse inputs from the dentate gyrus to CA3…
Mise en ligne : 29 May 2017
How Hyperarousal and Sleep Reactivity Are Represented in Different Adult Age Groups: Results from a Large Cohort Study on Insomnia.
Altena E, Chen IY, Daviaux Y, Ivers H, Philip P, Morin CM. How Hyperarousal and Sleep Reactivity Are Represented in Different Adult Age Groups: Results from a Large Cohort Study on Insomnia. Brain Sci. 2017 Apr 14;7(4). pii: E41. Abstract Hyperarousal is a 24-h state of elevated cognitive and physiological activation, and is a core…
Mise en ligne : 14 April 2017
Optimized labeling of membrane proteins for applications to super-resolution imaging in confined cellular environments using monomeric streptavidin.
Chamma I, Rossier O, Giannone G, Thoumine O, Sainlos M. Optimized labeling of membrane proteins for applications to super-resolution imaging in confined cellular environments using monomeric streptavidin. Nat Protoc. 2017 Apr;12(4):748-763 Abstract Recent progress in super-resolution imaging (SRI) has created a strong need to improve protein labeling with probes of small size that minimize the target-to-label…
Mise en ligne : 12 April 2017
D.Perrais, M. Rosendale inCell Reports
February 23rd, 2017 Rosendale M, Jullié D, Choquet D, Perrais D. (2017) Spatial and temporal regulation of receptor endocytosis in neuronal dendrites revealed by imaging of single vesicle formation. Cell Reports, Feb 21 David Perrais /IINS Bordeaux / Nano-scale organization, dynamics of synaptic proteins and membrane trafficking. Morgane Rosendale: Brain Research Institute RIKEN, Japon …
Mise en ligne : 23 February 2017