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© Pierrick Coupé, LABRI (CNRS/Bordeaux INP/Université de Bordeaux). Silhouettes : © rashadashurov/Stock.adobe.com

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Lifespan changes of the human brain in Alzheimer’s disease

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Arne Battefeld et al. in Cell Reports

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Mathieu Wolff & Seralynne Vann in JNeurosci

The Cognitive Thalamus as a gateway to mental representations. 

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Florent Laferrière et al. in Nature Neuroscience

Maladie de Charcot et maladie de Pick: portrait-robot des suspects

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Presenilin-mediated cleavage of APP regulates synaptotagmin-7 and presynaptic plasticity.

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Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models.

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A subcortical circuit linking the cerebellum to the basal ganglia engaged in vocal learning.

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Kellermayer, Ferreira, Dupuis, Groc et al. in Neuron

The nanoscale topography of GluN2-NMDA receptor subtypes tunes plasticity at glutamatergic synapses.

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Dentate Granule Neurons Generated During Perinatal Life Display Distinct Morphological Features Compared With Later-Born Neurons in the Mouse Hippocampus. Thomas Kerloch, Solène Clavreul, Adeline Goron, Djoher Nora Abrous, Emilie Pacary. Cereb Cortex. 2018 Sep 12. doi: 10.1093/cercor/bhy224.

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Véronique Pallet, Sophie Layé et al. in J Gerontol A Biol Sci Med Sci.

Polyphenols from grape and blueberry improve episodic memory in healthy elderly with lower level of memory performance: a bicentric double-blind, randomized, placebo-controlled clinical study. 

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Neuronal Activity and Intracellular Calcium Levels Regulate Intracellular Transport of Newly Synthesized AMPAR. 

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Didier Dulon et al. in Journal of clinical investigation

Clarin-1 gene transfer rescues auditory synaptopathy in model of Usher syndrome.

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nanoparticules - Didier Morin - INCIA - Bordeaux Neurocampus

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Acute exposure to zinc oxide nanoparticles critically disrupts operation of the respiratory neural network in neonatal rat.

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Eating memory?

RNA from Trained Aplysia Can Induce an Epigenetic Engram for Long-Term Sensitization in Untrained Aplysia,

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Thomas Pfeiffer, Valentin Nagerl et al. ineLife

Chronic 2P-STED imaging reveals high turnover of dendritic spines in the hippocampus in viv

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Serge Ahmed et al. in Molecular Psychiatry

Subthalamic nucleus inactivation prevents and reverses escalated cocaine use.

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François M. Lambert, Didier Le Ray et al. in eLife

Functional limb muscle innervation prior to cholinergic transmitter specification during early metamorphosis in Xenopus.

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P. Opazo, D. Choquet et al. dans Cell Reports

CaMKII metaplasticity drives Aβoligomers-mediated synaptotoxicity.

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Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium.

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Inhaling xenon ameliorates l-dopa-induced dyskinesia in experimental parkinsonism.

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Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory

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Marine Chazalon, Jérôme Baufreton et al. inCell Report

GAT-3 Dysfunction Generates Tonic Inhibition in External Globus Pallidus Neurons in Parkinsonian Rodents.

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Emilie Pacary, Olivier Nicole et al. in Mol Psychiatry

A novel role for CAMKIIβ in the regulation of cortical neuron migration: implications for neurodevelopmental disorders.

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Adult Hippocampal Neurogenesis in Human: Myth or Reality?

Lucas Benoit, Ummi Ciptasari, Joséphine Gay, Marie Letournel, Lorraine Madur, Morgane Raynaud From Abrous’s Lab

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Cyril Dejean & Cyril Herry in Biol Psychiatry

Neuronal Circuits for Fear Expression and Recovery: Recent Advances and Potential Therapeutic Strategies.

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Mathieu Bourdenx & Benjamin Dehay dans Acta Neuro

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Aline Desmedt, Aline Marighetto, P-V Piazza in Biol Psy

Abnormal Fear Memory as a Model for Posttraumatic Stress Disorder

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Temporal Memory and Its Enhancement by Estradiol Requires Surface Dynamics of Hippocampal CA1 N-Methyl-D-Aspartate Receptors.

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Mathieu Wolff, Fabien Alcaraz et al. dans The J of N

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Benjamin Dehay et al. in Movement Disorders

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The Endocannabinoid System: Pivotal Orchestrator of Obesity and Metabolic Disease. Mazier W, Saucisse N, Gatta-Cherifi B, Cota D. Trends Endocrinol Metab. 2015 Oct;26(10):524-37. doi: 10.1016/j.tem.2015.07.007. Review. Daniela Cota: The first reports of increased appetite induced by cannabis (also known as marijuana) in humans were documented in 300 AD. Pharmacological studies carried out in different animal models between the late seventies and the early nineties had further shown that peripheral or central administration of Δ9-tetrahydrocannabinol (THC), the main psychoactive component of marijuana, or other synthetic cannabinoids increased food intake, especially for palatable food. However, understanding of the biological mechanisms underlying the “munchies”…

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Yoon Cho, Cayzac S et al. in Neurobiol. Aging

Alzheimer’s disease mice lost in space!

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M.Chevalier, M.Thoby Brisson et al. in eNeuro

Sighing is healthy, but how does it work?

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