Moringa oleifera: A Tree of Life as a Promising Medicinal Plant for Neurodegenerative Diseases
J. Agric. Food Chem.. 2021-11-29; 69(48): 14358-14371
DOI: 10.1021/acs.jafc.1c04581
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Ghimire S(1), Subedi L(2), Acharya N(3), Gaire BP(2).
Author information:
(1)Department of Neuroscience, Institute of Neurodegenerative Diseases (IMN),
University of Bordeaux, 33076 Bordeaux, France.
(2)Department of Anesthesiology and Neurology, Shock Trauma and Anesthesiology
Research Center, University of Maryland School of Medicine, Baltimore, Maryland
21201, United States.
(3)Department of Animal Physiology, Institute of Biology, Leipzig University,
04103 Leipzig, Germany.
Moringa oleifera, popularly known as a miracle tree or tree of life, has been
extensively used as a functional food and nutritional asset worldwide.
Ethnomedicinal and traditional uses of M. oleifera indicate that this plant
might have a pleiotropic therapeutic efficacy against most human ailments. In
fact, M. oleifera is reported to have several pharmacological activities,
including antioxidant, antibacterial, antifungal, antidiabetic, antipyretic,
antiulcer, antispasmodic, antihypertensive, antitumor, hepatoprotective, and
cardiac stimulant properties. Recently, a few experimental studies reported the
neuroprotective effects of M. oleifera against Alzheimer’s disease, dementia,
Parkinson’s disease, stroke, and neurotoxicity-related symptoms. In addition,
several neuroprotective phytochemicals have been isolated from M. oleifera,
which signifies that it can have promising neuroprotective effects. Therefore,
this review aimed to explore the current updates and future prospective of
neuroprotective efficacies of M. oleifera.