Beyond the Cuvette: Redox Indicators in Biological Experiments

Pouvreau S(1)(2).

Author information:
(1)1 University of Bordeaux , Interdisciplinary Institute for Neuroscience,
UMR5297, Bordeaux, France .
(2)2 CNRS, Interdisciplinary Institute for Neuroscience , UMR5297, Bordeaux,
France .

Redox signaling is involved in numerous physiological and pathological processes
(cell cycle, gene transcription, calcium signaling, stress response,
ischemia-reperfusion injury, etc.). However, its exact role in cell biology and
physiology remains poorly understood, mostly due to the technical challenges
that the experimenter faces while trying to detect reactive oxygen species (ROS)
or redox species with adequate specificity, spatial, and temporal accuracy.
Recently, tremendous efforts have been put into the development of techniques
for redox detection. This Forum focuses on ex and in vivo live-imaging of ROS
and redox species using fluorescent dyes. Antioxid. Redox Signal. 25, 517-519.

DOI: 10.1089/ars.2016.6829
PMID: 27418437 [Indexed for MEDLINE]

Auteurs Bordeaux Neurocampus