Elisabete Augusto

Publications

• Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction
  Elisabete Augusto, Francisco Q. Gonçalves, Joana E. Real, Henrique B. Silva, Daniela Pochmann, Tiago S. Silva, Marco Matos, Nélio Gonçalves, Ângelo R. Tomé, Jiang-Fan Chen, Paula M. Canas, Rodrigo A. Cunha.
  Neurobiology of Disease. 2021-09-01. 157 : 105441.
  10.1016/j.nbd.2021.105441
• The integration of Gaussian noise by long-range amygdala inputs in frontal circuit promotes fear learning in mice
  Mattia Aime, Elisabete Augusto, Vladimir Kouskoff, Tiago Campelo, Christelle Martin, Yann Humeau, Nicolas Chenouard, Frederic Gambino.
  eLife. 2020-11-30. 9
  10.7554/elife.62594
• AMPAR-Dependent Synaptic Plasticity Initiates Cortical Remapping and Adaptive Behaviors during Sensory Experience
  Tiago Campelo, Elisabete Augusto, Nicolas Chenouard, Aron de Miranda, Vladimir Kouskoff, Come Camus, Daniel Choquet, Frédéric Gambino.
  Cell Reports. 2020-09-01. 32(9) : 108097.
  10.1016/j.celrep.2020.108097
• Can NMDA Spikes Dictate Computations of Local Networks and Behavior?
  Elisabete Augusto, Frédéric Gambino.
  Front. Mol. Neurosci.. 2019-09-27. 12
  10.3389/fnmol.2019.00238
• Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions
  Paula M. Canas, Lisiane O. Porciúncula, Ana Patrícia Simões, Elisabete Augusto, Henrique B. Silva, Nuno J. Machado, Nélio Gonçalves, Tiago M. Alfaro, Francisco Q. Gonçalves, Inês M. Araújo, Joana I. Real, Joana E. Coelho, Geanne M. Andrade, Ramiro D. Almeida, Jiang-Fan Chen, Attila Köfalvi, Paula Agostinho, Rodrigo A. Cunha.
  eNeuro. 2018-11-01. 5(6) : ENEURO.0385-18.2018.
  10.1523/eneuro.0385-18.2018
• Deletion of Adenosine A2A Receptors From Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia
  Marco Matos, Hai-Ying Shen, Elisabete Augusto, Yumei Wang, Catherine J. Wei, Yu Tian Wang, Paula Agostinho, Detlev Boison, Rodrigo A. Cunha, Jiang-Fan Chen.
  Biological Psychiatry. 2015-12-01. 78(11) : 763-774.
  10.1016/j.biopsych.2015.02.026
• Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory
  P Li, D Rial, P M Canas, J-H Yoo, W Li, X Zhou, Y Wang, G J P van Westen, M-P Payen, E Augusto, N Gonçalves, A R Tomé, Z Li, Z Wu, X Hou, Y Zhou, Ad PIJzerman, E S Boyden, R A Cunha, J Qu, J-F Chen.
  Mol Psychiatry. 2015-02-17. 20(11) : 1339-1349.
  10.1038/mp.2014.182
• Regulation of Fear Responses by Striatal and Extrastriatal Adenosine A2A Receptors in Forebrain
  Catherine J. Wei, Elisabete Augusto, Catarina A. Gomes, Philipp Singer, Yumei Wang, Detlev Boison, Rodrigo A. Cunha, Benjamin K. Yee, Jiang-Fan Chen.
  Biological Psychiatry. 2014-06-01. 75(11) : 855-863.
  10.1016/j.biopsych.2013.05.003
• Antagonistic Interaction between Adenosine A2A Receptors and Na+/K+-ATPase- 2 Controlling Glutamate Uptake in Astrocytes
  Marco Matos, Elisabete Augusto, Paula Agostinho, Rodrigo A. Cunha, Jiang-Fan Chen.
  J. Neurosci.. 2013-11-20. 33(47) : 18492-18502.
  10.1523/jneurosci.1828-13.2013
• Ecto-5′-Nucleotidase (CD73)-Mediated Formation of Adenosine Is Critical for the Striatal Adenosine A2A Receptor Functions
  E. Augusto, M. Matos, J. Sevigny, A. El-Tayeb, M. S. Bynoe, C. E. Muller, R. A. Cunha, J.-F. Chen.
  Journal of Neuroscience. 2013-07-10. 33(28) : 11390-11399.
  10.1523/jneurosci.5817-12.2013
• Genetic inactivation of the adenosine A2Areceptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis
  Shu-Qin Yao, Zheng-Zheng Li, Qing-Yuan Huang, Fang Li, Zhao-Wei Wang, Elisabete Augusto, Jin-Cai He, Xiao-Tong Wang, Jiang-Fan Chen, Rong-Yuan Zheng.
  Journal of Neurochemistry. 2012-08-23. 123(1) : 100-112.
  10.1111/j.1471-4159.2012.07807.x
• Astrocytic Adenosine A2A Receptors Control the Amyloid-ß Peptide-Induced Decrease of Glutamate Uptake
  Marco Matos, Elisabete Augusto, Nuno J. Machado, Alexandre dos Santos-Rodrigues, Rodrigo A. Cunha, Paula Agostinho.
  JAD. 2012-08-22. 31(3) : 555-567.
  10.3233/jad-2012-120469
• Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes
  Marco Matos, Elisabete Augusto, Alexandre Dos Santos-Rodrigues, Michael A. Schwarzschild, Jiang-Fan Chen, Rodrigo A. Cunha, Paula Agostinho.
  Glia. 2012-02-01. 60(5) : 702-716.
  10.1002/glia.22290
• Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: Involvement of oxidative stress and mitogen-activated protein kinase cascades
  M. Matos, E. Augusto, C.R. Oliveira, P. Agostinho.
  Neuroscience. 2008-10-01. 156(4) : 898-910.
  10.1016/j.neuroscience.2008.08.022