Membrane trafficking of post-synaptic cargo is a key determinant of synaptic transmission and synaptic plasticity. We describe here the latest developments in visualizing individual exocytosis and endocytosis events in neurons using pH-sensitive tags. We show how these tools help decipher the spatial and temporal regulation of membrane trafficking steps during synaptic plasticity.
Keywords: endocytosis; exocytosis; live cell fluorescence imaging; membrane trafficking; synaptic plasticity.
© 2023 The Authors.